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Gene Expression Data
Assay Details
Assay
Reference: J:203997 Krawchuk D, et al., FGF4 is a limiting factor controlling the proportions of primitive endoderm and epiblast in the ICM of the mouse blastocyst. Dev Biol. 2013 Dec 1;384(1):65-71
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6752543
Gene symbol: Gata6
Gene name: GATA binding protein 6
Results
Specimen 1F.F': embryonic day 3.75 (more )
Note: Triple labeled: green - Gata6; red - Nanog (assay MGI:6752539); blue - Cdx2 (assay MGI:6752541).
Structure Level Pattern Image Note
TS5: inner cell mass Present Regionally restricted 1F , 1F' Expression in primitive endoderm progenitors
Specimen 1G,G': embryonic day 3.75; Fgf4tm1.3Mrt/Fgf4+ (more )
Note: Triple labeled: green - Gata6; red - Nanog (assay MGI:6752539); blue - Cdx2 (assay MGI:6752541).
Structure Level Pattern Image Note
TS5: inner cell mass Present Regionally restricted 1G' , 1G No significant reduction in proportion of peimitive endoderm progenitors compared with wild type embryos.
Specimen 1H,H': embryonic day 3.75; Fgf4tm1.3Mrt/Fgf4tm1.3Mrt (more )
Note: Triple labeled: green - Gata6; red - Nanog (assay MGI:6752539); blue - Cdx2 (assay MGI:6752541).
Structure Level Pattern Image Note
TS5: inner cell mass Absent 1H' , 1H
Specimen 1I,I': embryonic day 3.75; Fgf4tm1.2Mrt/Fgf4+, Tg(Zp3-cre)93Knw/0 (more )
Note: Conditional mutant. Triple labeled: green - Gata6; red - Nanog (assay MGI:6752539); blue - Cdx2 (assay MGI:6752541).
Structure Level Pattern Image Note
TS5: inner cell mass Weak Regionally restricted 1I' , 1I Authors report a reduction in proportion of primitive endoderm progenitors.
Specimen 1J,J': embryonic day 3.75; Fgf4tm1.2Mrt/Fgf4tm1.3Mrt, Tg(Zp3-cre)93Knw/0 (more )
Note: Conditional mutant. Triple labeled: green - Gata6; red - Nanog (assay MGI:6752539); blue - Cdx2 (assay MGI:6752541).
Structure Level Pattern Image Note
TS5: inner cell mass Absent 1J' , 1J
Specimen 1K,K": embryonic day 3.25 (more )
Note: Triple labeled: green - Gata6; red - Nanog (assay MGI:6752539); blue - Cdx2 (assay MGI:6752541).
Structure Level Pattern Image Note
TS4: inner cell mass Present Ubiquitous 1K" , 1K Expression in all inner cell mass cells.
Specimen 1L,L": embryonic day 3.25; Fgf4tm1.2Mrt/Fgf4tm1.3Mrt, Tg(Zp3-cre)93Knw/0 (more )
Note: Conditional mutant. Triple labeled: green - Gata6; red - Nanog (assay MGI:6752539); blue - Cdx2 (assay MGI:6752541).
Structure Level Pattern Image Note
TS4: inner cell mass Present Ubiquitous 1L" , 1L Expression not affected compared with wild type embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory