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Gene Expression Data
Assay Details
Assay
Reference: J:203997 Krawchuk D, et al., FGF4 is a limiting factor controlling the proportions of primitive endoderm and epiblast in the ICM of the mouse blastocyst. Dev Biol. 2013 Dec 1;384(1):65-71
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6752539
Gene symbol: Nanog
Gene name: Nanog homeobox
Antibody: anti-Nanog
Results
Specimen 1A: embryonic day 3.75 (more )
Note: Triple labeled: red - Nanog; green - Sox17 (assay MGI:6752540); blue - Cdx2 (assay MGI:6752541).
Structure Level Pattern Image Note
TS5: inner cell mass Present Regionally restricted 1A Expression in epiblast progenitors. randomly distributed in inner cell mass.
Specimen 1B: embryonic day 3.75; Fgf4tm1.3Mrt/Fgf4+ (more )
Note: Triple labeled: red - Nanog; green - Sox17 (assay MGI:6752540); blue - Cdx2 (assay MGI:6752541).
Structure Level Pattern Image Note
TS5: inner cell mass Present 1B
Specimen 1C: embryonic day 3.75; Fgf4tm1.3Mrt/Fgf4tm1.3Mrt (more )
Note: Triple labeled: red - Nanog; green - Sox17 (assay MGI:6752540); blue - Cdx2 (assay MGI:6752541).
Structure Level Pattern Image Note
TS5: inner cell mass Present Ubiquitous 1C Expression in all inner cell mass cells.
Specimen 1D: embryonic day 3.75; Fgf4tm1.2Mrt/Fgf4+, Tg(Zp3-cre)93Knw/0 (more )
Note: Conditional mutant. Triple labeled: red - Nanog; green - Sox17 (assay MGI:6752540); blue - Cdx2 (assay MGI:6752541).
Structure Level Pattern Image Note
TS5: inner cell mass Present Regionally restricted 1D Authors report an increase in the proportion of epiblast progenitors
Specimen 1E: embryonic day 3.75; Fgf4tm1.2Mrt/Fgf4tm1.3Mrt, Tg(Zp3-cre)93Knw/0 (more )
Note: Conditional mutant. Triple labeled: red - Nanog; green - Sox17 (assay MGI:6752540); blue - Cdx2 (assay MGI:6752541).
Structure Level Pattern Image Note
TS5: inner cell mass Present 1E
Specimen 1F: embryonic day 3.75 (more )
Note: Triple labeled: red - Nanog; green - Gata6 (assay MGI:6752543); blue - Cdx2 (assay MGI:6752541).
Structure Level Pattern Image Note
TS5: inner cell mass Present Regionally restricted 1F Expression in epiblast progenitors. randomly distributed in inner cell mass.
Specimen 1G: embryonic day 3.75; Fgf4tm1.3Mrt/Fgf4+ (more )
Note: Triple labeled: red - Nanog; green - Gata6 (assay MGI:6752543); blue - Cdx2 (assay MGI:6752541).
Structure Level Pattern Image Note
TS5: inner cell mass Present 1G
Specimen 1H: embryonic day 3.75; Fgf4tm1.3Mrt/Fgf4tm1.3Mrt (more )
Note: Triple labeled: red - Nanog; green - Gata6 (assay MGI:6752543); blue - Cdx2 (assay MGI:6752541).
Structure Level Pattern Image Note
TS5: inner cell mass Present Ubiquitous 1H Expression in all inner cell mass cells.
Specimen 1I: embryonic day 3.75; Fgf4tm1.2Mrt/Fgf4+, Tg(Zp3-cre)93Knw/0 (more )
Note: Conditional mutant. Triple labeled: red - Nanog; green - Gata6 (assay MGI:6752543); blue - Cdx2 (assay MGI:6752541).
Structure Level Pattern Image Note
TS5: inner cell mass Present Regionally restricted 1I Authors report an increase in the proportion of epiblast progenitors
Specimen 1J: embryonic day 3.75; Fgf4tm1.2Mrt/Fgf4tm1.3Mrt, Tg(Zp3-cre)93Knw/0 (more )
Note: Conditional mutant. Triple labeled: red - Nanog; green - Gata6 (assay MGI:6752543); blue - Cdx2 (assay MGI:6752541).
Structure Level Pattern Image Note
TS5: inner cell mass Present Ubiquitous 1J Expression in all inner cell mass cells.
Specimen 1K,K': embryonic day 3.25 (more )
Note: Triple labeled: red - Nanog; green - Gata6 (assay MGI:6752543); blue - Cdx2 (assay MGI:6752541).
Structure Level Pattern Image Note
TS4: inner cell mass Present 1K' , 1K
Specimen 1L,L': embryonic day 3.25; Fgf4tm1.2Mrt/Fgf4tm1.3Mrt, Tg(Zp3-cre)93Knw/0 (more )
Note: Conditional mutant. Triple labeled: red - Nanog; green - Gata6 (assay MGI:6752543); blue - Cdx2 (assay MGI:6752541).
Structure Level Pattern Image Note
TS4: inner cell mass Present 1L , 1L'
Specimen 4A: embryonic day 4.5 (more )
Note: Triple labeled: red - Nanog; green - Sox17 (assay MGI:6752540); blue - Cdx2 (assay MGI:6752541).
Structure Level Pattern Image Note
TS6: epiblast Present 4A
Specimen 4B: embryonic day 4.5; Fgf4tm1.3Mrt/Fgf4+ (more )
Note: Triple labeled: red - Nanog; green - Sox17 (assay MGI:6752540); blue - Cdx2 (assay MGI:6752541).
Structure Level Pattern Image Note
TS6: epiblast Present 4B
Specimen 4C: embryonic day 4.5; Fgf4tm1.2Mrt/Fgf4+, Tg(Zp3-cre)93Knw/0 (more )
Note: Conditional mutant. Triple labeled: red - Nanog; green - Sox17 (assay MGI:6752540); blue - Cdx2 (assay MGI:6752541).
Structure Level Pattern Image Note
TS6: epiblast Present 4C
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory