About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:271138 Coulter ME, et al., The ESCRT-III Protein CHMP1A Mediates Secretion of Sonic Hedgehog on a Distinctive Subtype of Extracellular Vesicles. Cell Rep. 2018 Jul 24;24(4):973-986.e8
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6726349
Gene symbol: Chmp1a
Gene name: charged multivesicular body protein 1A
Antibody: Chmp1a antibody (15761-1-AP)
Detection system: Alexa Fluor
Results
Specimen 2B Chmp1a: postnatal day 0 (more )
Note: Double labeled: red - Chmp1a; green - Calbindin (Calb1 assay MGI:6726348).
Structure Level Pattern Image Note
TS27: cerebellum Purkinje cell layer Present Regionally restricted 2B Chmp1a , 2B Merge Expression in Purkinje cell cytoplasm and dendrites; expression absent from nucleus.
TS27: cerebellum external granule cell layer Absent 2B Merge , 2B Chmp1a
Specimen 2E Chmp1a: embryonic day 14.5 (more )
Note: Triple labeled: red - Chmp1a; green - Ctip2 (Bcl11b assay MGI:6726345); pink - Sox2 (assay MGI:6726350).
Structure Level Pattern Image Note
TS22: cortical plate Present 2E Chmp1a , 2E Merge Expression in postmitotic neurons in cerebral cortex.
TS22: cerebral cortex subventricular zone Absent 2E Chmp1a , 2E Merge No expression in progenitors.
TS22: cerebral cortex ventricular layer Absent 2E Chmp1a , 2E Merge No expression in progenitors.
Specimen S3A Chmp1a: postnatal day 0 (more )
Note: Triple labeled: red - Chmp1a; green - Aqp1 (assay MGI:6726354); blue - Hoechst.
Structure Level Pattern Image Note
TS27: 4th ventricle choroid plexus epithelium Present Punctate S3A Punctate expression in epithelial cells of hindbrain choroid plexus.
Specimen S3D Control: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: cerebellum Present S3D CHMP1A WT
Specimen S3D Chmp1a null: postnatal day 0; Chmp1aGt(XC472)Byg/Chmp1aGt(XC472)Byg (more )
Structure Level Pattern Image Note
TS27: cerebellum Absent S3D CHMP1A Chmp1a null
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory