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Gene Expression Data
Assay Details
Assay
Reference: J:271138 Coulter ME, et al., The ESCRT-III Protein CHMP1A Mediates Secretion of Sonic Hedgehog on a Distinctive Subtype of Extracellular Vesicles. Cell Rep. 2018 Jul 24;24(4):973-986.e8
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6726345
Gene symbol: Bcl11b
Gene name: B cell leukemia/lymphoma 11B
Antibody: anti-CTIP2 [25B6] (ab18465)
Detection system: Alexa Fluor
Results
Specimen 1E Ctip2 Control: embryonic day 18.5 (more )
Note: Double labeled: green - CTIP2 (Bcl11b); red - Cux1 (assay MGI:6726346).
Structure Level Pattern Image Note
TS26: neocortex Present Regionally restricted 1E Control Expression in deep cortical layers (layers V-VI).
Specimen 1E Ctip2 Chmp1a null: embryonic day 18.5; Chmp1aGt(XC472)Byg/Chmp1aGt(XC472)Byg (more )
Note: Double labeled: green - CTIP2 (Bcl11b); red - Cux1 (assay MGI:6726346).
Structure Level Pattern Image Note
TS26: neocortex Weak 1E Chmp1a null Authors report cortical plate is 13% thinner than in controls.
Specimen 2E Ctip2: embryonic day 14.5 (more )
Note: Triple labeled: green - CTIP2 (Bcl11b); pink - Sox2 (assay MGI:6726350); red - Chmp1a (assay MGI:6726349).
Structure Level Pattern Image Note
TS22: cortical plate Present 2E Chmp1a Expression in postmitotic neurons in cerebral cortex.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/28/2024
MGI 6.13 		The Jackson Laboratory