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Gene Expression Data
Assay Details
Assay
Reference: J:296652 Chan WH, et al., Differences in CART expression and cell cycle behavior discriminate sympathetic neuroblast from chromaffin cell lineages in mouse sympathoadrenal cells. Dev Neurobiol. 2016 Feb;76(2):137-49
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6726289
Gene symbol: Cartpt
Gene name: CART prepropeptide
Antibody: anti-CART
Detection system: Secondary antibody coupled to DyLight 594
Assay notes: Fixative was Zamboni's fixative (2% formaldehyde and 15% saturated picric acid).
Results
Specimen 1C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: abdominal segment of trunk Present Single cells 1C Positive cells are seen around the dorsal aorta in sympathoadrenal progenitor cells.
Specimen 2C: embryonic day 11.5 (more )
Note: Triple labeled: red - Cartpt; green - Th (assay MGI:6726288); magenta - Sox10 (assay MGI:6726290).
Structure Level Pattern Image Note
TS19: abdominal segment of trunk Present Single cells 2A , 2C A few positive cells are seen around the dorsal aorta in sympathoadrenal progenitor cells.
Specimen 2G: embryonic day 12.5 (more )
Note: Triple labeled: red - Cartpt; green - Th (assay MGI:6726288); magenta - Pmnt (assay MGI:6726291).
Structure Level Pattern Image Note
TS20: abdominal segment of trunk Present Single cells 2G , 2E Positive cells are seen around the dorsal aorta in sympathoadrenal progenitor cells.
Specimen 2K: embryonic day 13.5 (more )
Note: Triple labeled: red - Cartpt; green - Th (assay MGI:6726288); magenta - Pmnt (assay MGI:6726291).
Structure Level Pattern Image Note
TS21: sympathetic ganglion Present Regionally restricted 2I , 2K Expression is in the sympathetic neuroblasts in the developing suprarenal prevertebral ganglia.
TS21: adrenal gland Present Regionally restricted 2K , 2I Expression is in a few cells at the interface between the suprarenal ganglion and the adrenal medulla.
Specimen 2O: embryonic day 14.5 (more )
Note: Triple labeled: red - Cartpt; green - Th (assay MGI:6726288); magenta - Pmnt (assay MGI:6726291).
Structure Level Pattern Image Note
TS22: sympathetic ganglion Strong 2M , 2O
TS22: adrenal medulla Present Single cells 2O , 2M Expression is in a few chromaffin cells.
Specimen 2S: embryonic day 15.5 (more )
Note: Triple labeled: red - Cartpt; green - Th (assay MGI:6726288); magenta - Pmnt (assay MGI:6726291).
Structure Level Pattern Image Note
TS23: sympathetic ganglion Strong 2Q , 2S
TS23: adrenal medulla Present Regionally restricted 2S , 2Q Expression is in chromaffin cells.
Specimen 2W: embryonic day 16.5 (more )
Note: Triple labeled: red - Cartpt; green - Th (assay MGI:6726288); magenta - Pmnt (assay MGI:6726291).
Structure Level Pattern Image Note
TS24: sympathetic ganglion Strong 2U , 2W
TS24: adrenal medulla Present Regionally restricted 2W , 2U Expression is in chromaffin cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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