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Gene Expression Data
Assay Details
Assay
Reference: J:296652 Chan WH, et al., Differences in CART expression and cell cycle behavior discriminate sympathetic neuroblast from chromaffin cell lineages in mouse sympathoadrenal cells. Dev Neurobiol. 2016 Feb;76(2):137-49
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6726288
Gene symbol: Th
Gene name: tyrosine hydroxylase
Antibody: anti-TH
Detection system: Secondary antibody coupled to fluorescein
Assay notes: Fixative was Zamboni's fixative (2% formaldehyde and 15% saturated picric acid).
Results
Specimen 1B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: abdominal segment of trunk Present Single cells 1B Positive cells are seen around the dorsal aorta in sympathoadrenal progenitor cells.
Specimen 2B: embryonic day 11.5 (more )
Note: Triple labeled: green - Th; red - Cartpt (assay MGI:6726289); magenta - Sox10 (assay MGI:6726290).
Structure Level Pattern Image Note
TS19: abdominal segment of trunk Present Single cells 2B , 2A Positive cells are seen around the dorsal aorta in sympathoadrenal progenitor cells.
Specimen 2F: embryonic day 12.5 (more )
Note: Triple labeled: green - Th; red - Cartpt (assay MGI:6726289); magenta - Pnmt (assay MGI:6726291).
Structure Level Pattern Image Note
TS20: abdominal segment of trunk Present Single cells 2F , 2E Positive cells are seen around the dorsal aorta in sympathoadrenal progenitor cells. Expression is higher in cells located further away.
Specimen 2J: embryonic day 13.5 (more )
Note: Triple labeled: green - Th; red - Cartpt (assay MGI:6726289); magenta - Pnmt (assay MGI:6726291).
Structure Level Pattern Image Note
TS21: adrenal gland Strong Regionally restricted 2I , 2J Expression is in the adrenal medulla.
TS21: sympathetic ganglion Weak
Specimen 2N: embryonic day 14.5 (more )
Note: Triple labeled: green - Th; red - Cartpt (assay MGI:6726289); magenta - Pnmt (assay MGI:6726291).
Structure Level Pattern Image Note
TS22: adrenal medulla Strong 2M , 2N
TS22: sympathetic ganglion Present 2M , 2N
Specimen 2R: embryonic day 15.5 (more )
Note: Triple labeled: green - Th; red - Cartpt (assay MGI:6726289); magenta - Pnmt (assay MGI:6726291).
Structure Level Pattern Image Note
TS23: adrenal medulla Strong 2R , 2Q
TS23: sympathetic ganglion Present 2R , 2Q
Specimen 2V: embryonic day 16.5 (more )
Note: Triple labeled: green - Th; red - Cartpt (assay MGI:6726289); magenta - Pnmt (assay MGI:6726291).
Structure Level Pattern Image Note
TS24: adrenal medulla Strong 2U , 2V
TS24: sympathetic ganglion Present 2U , 2V
Specimen not shown E10.5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: abdominal segment of trunk Absent There are no positive cells in the upper abdominal cavity.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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