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Gene Expression Data
Assay Details
Assay
Reference: J:177992 Nowell CS, et al., Foxn1 regulates lineage progression in cortical and medullary thymic epithelial cells but is dispensable for medullary sublineage divergence. PLoS Genet. 2011 Nov;7(11):e1002348
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6725795
Gene symbol: Krt8
Gene name: keratin 8
Antibody: TROMA 1
Results
Specimen 2B K8: postnatal week 6; Foxn1tm1.1Cbln/Foxn1+ (more )
Note: Double labeled: red - K8 (Krt8); green - K5 (Krt5 assay MGI:6725794).
Structure Level Pattern Image Note
TS28: thymus epithelium Present Regionally restricted 2B Authors report overtly normal cortical and medullary compartments.
Specimen 4B R/- K8: postnatal; Foxn1tm1.1Cbln/Foxn1tm1Tbo, Gt(ROSA)26Sortm2(cre/ERT2)Brn/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Double labeled: red - K8 (Krt8); green - K5 (Krt5 assay MGI:6725794).
Structure Level Pattern Image Note
TS28: thymus epithelium Present Regionally restricted 4B R/- K8/K5
Specimen 4B -/- K8: postnatal; Foxn1tm1Tbo/Foxn1tm1Tbo (more )
Note: Double labeled: red - K8 (Krt8); green - K5 (Krt5 assay MGI:6725794).
Structure Level Pattern Image Note
TS28: thymus epithelium Present Regionally restricted 4B -/- K8/K5
Specimen 5A -/- K8 (upper): embryonic day 13.5; Foxn1tm1Tbo/Foxn1tm1Tbo (more )
Note: Double labeled: red - K8 (Krt8); green - K5 (Krt5 assay MGI:6725794).
Structure Level Pattern Image Note
TS21: thymus primordium Present Regionally restricted 5A -/- K5/K8
Specimen 5A R/+ K8 (upper): embryonic day 13.5; Foxn1tm1.1Cbln/Foxn1+ (more )
Note: Double labeled: red - K8 (Krt8); green - K5 (Krt5 assay MGI:6725794).
Structure Level Pattern Image Note
TS21: thymus primordium Present Regionally restricted 5A R/+ K5/K8
Specimen 5A -/- K8 (lower): embryonic day 13.5; Foxn1tm1Tbo/Foxn1tm1Tbo (more )
Note: Double labeled: red - K8 (Krt8); green - Cldn4 (assay MGI:6725806).
Structure Level Pattern Image Note
TS21: thymus primordium Present Regionally restricted 5A -/- Cldn4/K8
Specimen 5A R/+ K8 (lower): embryonic day 13.5; Foxn1tm1.1Cbln/Foxn1+ (more )
Note: Double labeled: red - K8 (Krt8); green - Cldn4 (assay MGI:6725806).
Structure Level Pattern Image Note
TS21: thymus primordium Present Regionally restricted 5A R/+ Cldn4/K8
Specimen S5A -/- K8: embryonic day 15.5; Foxn1tm1Tbo/Foxn1tm1Tbo (more )
Note: Double labeled: red - K8 (Krt8); green - K5 (Krt5 assay MGI:6725794).
Structure Level Pattern Image Note
TS23: thymus primordium Present Regionally restricted S5A -/- K8 , S5A -/- merge
Specimen S5A R/+ K8: embryonic day 15.5; Foxn1tm1.1Cbln/Foxn1+ (more )
Note: Double labeled: red - K8 (Krt8); green - K5 (Krt5 assay MGI:6725794).
Structure Level Pattern Image Note
TS23: thymus primordium Present Regionally restricted S5A R/+ K8 , S5A R/+ merge
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory