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Gene Expression Data
Assay Details
Assay
Reference: J:230729 Shafaq-Zadah M, et al., Persistent cell migration and adhesion rely on retrograde transport of beta(1) integrin. Nat Cell Biol. 2016 Jan;18(1):54-64
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6719394
Gene symbol: Itgb1
Gene name: integrin beta 1 (fibronectin receptor beta)
Results
Specimen S3a 6 dpc Rab6+/- B1 integrin: embryonic day 6.0; Rab6atm1.2Ics/Rab6a+ (more )
Note: Triple labeled: red - B1 integrin (Itgb1); green - Gata4 (assay MGI:6719393); blue - laminin.
Structure Level Pattern Image Note
TS8: egg cylinder Present S3a 6 dpc Rab6(+/-) B1 integrin , S3a 6 dpc Rab6(+/-) Merge At 6 dpc, all embryos with apparently healthy morphology were genotyped as Rab6a+/-.
Specimen S3b B1 integrin: embryonic day 5.5; Rab6atm1.2Ics/Rab6a+ (more )
Note: Triple labeled: red - B1 integrin (Itgb1); green - Rab6a (assay MGI:6719395); blue - DAPI.
Structure Level Pattern Image Note
TS7: egg cylinder Present S3b Merge , S3b B1 integrin
Specimen 3d Rab6+/- B1 integrin: embryonic day 5.5; Rab6atm1.2Ics/Rab6a+ (more )
Note: Triple labeled: red - B1 integrin (Itgb1); green - Oct4 (Pou5f1 assay MGI:6719396); white - laminin.
Structure Level Pattern Image Note
TS7: egg cylinder Present 3d Rab6+/- (merge) , 3d Rab6+/- B1 integrin
Specimen 3d Rab6-/- B1 integrin: embryonic day 5.5; Rab6atm1.2Ics/Rab6atm1.2Ics (more )
Note: Triple labeled: red - B1 integrin (Itgb1); green - Oct4 (Pou5f1 assay MGI:6719396); white - laminin.
Structure Level Pattern Image Note
TS7: egg cylinder Present 3d Rab6-/- (merge) , 3d Rab6-/- B1 integrin
Specimen 3e Rab6+/- B1 integrin: embryonic day 5.5; Rab6atm1.2Ics/Rab6a+ (more )
Note: Double labeled: red - B1 integrin (Itgb1); green - laminin.
Structure Level Pattern Image Note
TS7: basement membrane Present Regionally restricted 3e Rab6+/- B1 integrin , 3e Rab6+/- (merge) Enrichment of expression at basement membrane.
Specimen 3e Rab6-/- B1 integrin: embryonic day 5.5; Rab6atm1.2Ics/Rab6atm1.2Ics (more )
Note: Double labeled: red - B1 integrin (Itgb1); green - laminin.
Structure Level Pattern Image Note
TS7: epiblast Present Regionally restricted 3e Rab6-/- (merge) , 3e Rab6-/- B1 integrin Authors report a homogenous membrane distribution of expression.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory