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Gene Expression Data
Assay Details
Assay
Reference: J:297267 Tang Q, et al., Gfi1-GCE inducible Cre line for hair cell-specific gene manipulation in mouse inner ear. Genesis. 2019 Sep;57(9):e23304
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6717273
Gene symbol: Sox2
Gene name: SRY (sex determining region Y)-box 2
Antibody: Anti-Sox2 (Y-17; sc-17320)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 5c - WT - E13.5 - s/u: embryonic day 13.5 (more )
Note: Wild type control; also labeled with DAPI (blue).
Structure Level Pattern Image Note
TS21: saccule Present Regionally restricted 5c WT E13.5 upper left Expression is seen in the supporting cells.
TS21: utricle Present Regionally restricted 5c WT E13.5 upper left Expression is seen in the supporting cells.
Specimen 5c - WT - E13.5 - cd: embryonic day 13.5 (more )
Note: Wild type control; also labeled with DAPI (blue).
Structure Level Pattern Image Note
TS21: cochlear duct Present Regionally restricted 5c WT E13.5 lower left Expression is seen in the supporting cells.
Specimen 5c - WT - E14.5 - u: embryonic day 14.5 (more )
Note: Wild type control; also labeled with DAPI (blue).
Structure Level Pattern Image Note
TS22: utricle Present Regionally restricted 5c WT E14.5 right Expression is seen in the supporting cells.
Specimen 5c - hom - E13.5 - u: embryonic day 13.5; Gfi1tm2.1(GFP/cre/ERT2)Gan/Gfi1tm2.1(GFP/cre/ERT2)Gan (more )
Note: Triple labeled: red - Sox2; green - Gfi1 reporter (assay MGI:6717266); blue - DAPI.
Structure Level Pattern Image Note
TS21: utricle Present Regionally restricted 5c hom E13.5 upper left Expression is seen in the supporting cells; no differences in expression were observed between wild type and the mutants.
Specimen 5c - hom - E13.5 - cd: embryonic day 13.5; Gfi1tm2.1(GFP/cre/ERT2)Gan/Gfi1tm2.1(GFP/cre/ERT2)Gan (more )
Note: Triple labeled: red - Sox2; green - Gfi1 reporter (assay MGI:6717266); blue - DAPI.
Structure Level Pattern Image Note
TS21: cochlear duct Present Regionally restricted 5c hom E13.5 lower left Expression is seen in the supporting cells; no differences in expression were observed between wild type and the mutants.
Specimen 5c - hom - E13.5 - ac/lc: embryonic day 13.5; Gfi1tm2.1(GFP/cre/ERT2)Gan/Gfi1tm2.1(GFP/cre/ERT2)Gan (more )
Note: Triple labeled: red - Sox2; green - Gfi1 reporter (assay MGI:6717266); blue - DAPI.
Structure Level Pattern Image Note
TS21: superior semicircular canal Present Regionally restricted 5c hom E13.5 right Expression is seen in the supporting cells of the anterior crista; no differences in expression were observed between wild type and the mutants.
TS21: lateral semicircular canal Present Regionally restricted 5c hom E13.5 right Expression is seen in the supporting cells of the lateral crista; no differences in expression were observed between wild type and the mutants.
Specimen 5c - hom - E14.5 - lc/ac: embryonic day 14.5; Gfi1tm2.1(GFP/cre/ERT2)Gan/Gfi1tm2.1(GFP/cre/ERT2)Gan (more )
Note: Triple labeled: red - Sox2; green - Gfi1 reporter (assay MGI:6717266); blue - DAPI.
Structure Level Pattern Image Note
TS22: lateral semicircular canal Present Regionally restricted 5c hom E14.5 upper left Expression is seen in the supporting cells of the lateral crista; no differences in expression were observed between wild type and the mutants.
TS22: superior semicircular canal Present Regionally restricted 5c hom E14.5 upper left Expression is seen in the supporting cells of the anterior crista; no differences in expression were observed between wild type and the mutants.
Specimen 5c - hom - E14.5 - u: embryonic day 14.5; Gfi1tm2.1(GFP/cre/ERT2)Gan/Gfi1tm2.1(GFP/cre/ERT2)Gan (more )
Note: Triple labeled: red - Sox2; green - Gfi1 reporter (assay MGI:6717266); blue - DAPI.
Structure Level Pattern Image Note
TS22: utricle Present Regionally restricted 5c hom E14.5 lower left Expression is seen in the supporting cells; no differences in expression were observed between wild type and the mutants.
Specimen 5c - hom - E14.5 - cd: embryonic day 14.5; Gfi1tm2.1(GFP/cre/ERT2)Gan/Gfi1tm2.1(GFP/cre/ERT2)Gan (more )
Note: Triple labeled: red - Sox2; green - Gfi1 reporter (assay MGI:6717266); blue - DAPI.
Structure Level Pattern Image Note
TS22: cochlear duct Present Regionally restricted 5c hom E14.5 right Expression is seen in the supporting cells; no differences in expression were observed between wild type and the mutants.
Specimen 5c - WT - E15.5 - u/s: embryonic day 15.5 (more )
Note: Wild type control; also labeled with DAPI (blue).
Structure Level Pattern Image Note
TS23: utricle Present Regionally restricted 5c WT E15.5 left Expression is seen in the supporting cells.
TS23: saccule Present Regionally restricted 5c WT E15.5 left Expression is seen in the supporting cells.
Specimen 5c - WT - E15.5 - cd: embryonic day 15.5 (more )
Note: Wild type control; also labeled with DAPI (blue).
Structure Level Pattern Image Note
TS23: cochlear duct Present Regionally restricted 5c WT E15.5 right Expression is seen in the supporting cells.
Specimen 5c - WT - E17.5 - u: embryonic day 17.5 (more )
Note: Wild type control; also labeled with DAPI (blue).
Structure Level Pattern Image Note
TS25: utricle Present Regionally restricted 5c WT E17.5 right Expression is seen in the supporting cells.
Specimen 5c - hom - E15.5 - lc/ac: embryonic day 15.5; Gfi1tm2.1(GFP/cre/ERT2)Gan/Gfi1tm2.1(GFP/cre/ERT2)Gan (more )
Note: Triple labeled: red - Sox2; green - Gfi1 reporter (assay MGI:6717266); blue - DAPI.
Structure Level Pattern Image Note
TS23: lateral semicircular canal Present Regionally restricted 5c hom E15.5 upper left Expression is seen in the supporting cells of the lateral crista; no differences in expression were observed between wild type and the mutants.
TS23: superior semicircular canal Present Regionally restricted 5c hom E15.5 upper left Expression is seen in the supporting cells of the anterior crista; no differences in expression were observed between wild type and the mutants.
Specimen 5c - hom - E15.5 - s: embryonic day 15.5; Gfi1tm2.1(GFP/cre/ERT2)Gan/Gfi1tm2.1(GFP/cre/ERT2)Gan (more )
Note: Triple labeled: red - Sox2; green - Gfi1 reporter (assay MGI:6717266); blue - DAPI.
Structure Level Pattern Image Note
TS23: saccule Present Regionally restricted 5c hom E15.5 lower left Expression is seen in the supporting cells; no differences in expression were observed between wild type and the mutants.
Specimen 5c - hom - E15.5 - u: embryonic day 15.5; Gfi1tm2.1(GFP/cre/ERT2)Gan/Gfi1tm2.1(GFP/cre/ERT2)Gan (more )
Note: Triple labeled: red - Sox2; green - Gfi1 reporter (assay MGI:6717266); blue - DAPI.
Structure Level Pattern Image Note
TS23: utricle Present Regionally restricted 5c hom E15.5 lower center Expression is seen in the supporting cells; no differences in expression were observed between wild type and the mutants.
Specimen 5c - hom - E15.5 - cd: embryonic day 15.5; Gfi1tm2.1(GFP/cre/ERT2)Gan/Gfi1tm2.1(GFP/cre/ERT2)Gan (more )
Note: Triple labeled: red - Sox2; green - Gfi1 reporter (assay MGI:6717266); blue - DAPI.
Structure Level Pattern Image Note
TS23: cochlear duct Present Regionally restricted 5c hom E15.5 right Expression is seen in the supporting cells; no differences in expression were observed between wild type and the mutants.
Specimen 5c - hom - E17.5 - u/s: embryonic day 17.5; Gfi1tm2.1(GFP/cre/ERT2)Gan/Gfi1tm2.1(GFP/cre/ERT2)Gan (more )
Note: Triple labeled: red - Sox2; green - Gfi1 reporter (assay MGI:6717266); blue - DAPI.
Structure Level Pattern Image Note
TS25: utricle Present Regionally restricted 5c hom E17.5 left Expression is seen in the supporting cells; no differences in expression were observed between wild type and the mutants.
TS25: saccule Present Regionally restricted 5c hom E17.5 left Expression is seen in the supporting cells; no differences in expression were observed between wild type and the mutants.
Specimen 5c - hom - E17.5 - cd: embryonic day 17.5; Gfi1tm2.1(GFP/cre/ERT2)Gan/Gfi1tm2.1(GFP/cre/ERT2)Gan (more )
Note: Triple labeled: red - Sox2; green - Gfi1 reporter (assay MGI:6717266); blue - DAPI.
Structure Level Pattern Image Note
TS25: cochlear duct Present Regionally restricted 5c hom E17.5 right Expression is seen in the supporting cells; no differences in expression were observed between wild type and the mutants.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
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