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Gene Expression Data
Assay Details
Assay
Reference: J:241850 Naiman N, et al., Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development. Dev Cell. 2017 May 22;41(4):349-365.e3
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6711822
Gene symbol: Tnc
Gene name: tenascin C
Antibody: MAb MTn 12 (#T3413)
Detection system: Secondary antibody coupled to DyLight
Results
Specimen 2O: embryonic day 18.5; Pax2tm1.1Akio/Pax2+, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: red - Tnc; green - Vim (assay MGI:6711820); blue - Acta2 (assay MGI:6711822)
Structure Level Pattern Image Note
TS26: renal capsule Present 2O
Specimen 2P: embryonic day 18.5; Pax2tm1.1Akio/Pax2tm1.2Akio, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: red - Tnc; green - Vim (assay MGI:6711820); blue - Acta2 (assay MGI:6711822)
Structure Level Pattern Image Note
TS26: renal capsule Present 2P Renal interstitium development is largely normal in the mutants even without nephron formation.
Specimen 2O': embryonic day 18.5; Pax2tm1.1Akio/Pax2+, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: red - Tnc; green - Vim (assay MGI:6711820); blue - Acta2 (assay MGI:6711822)
Structure Level Pattern Image Note
TS26: renal cortical interstitium Present 2O'
Specimen 2P': embryonic day 18.5; Pax2tm1.1Akio/Pax2tm1.2Akio, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: red - Tnc; green - Vim (assay MGI:6711820); blue - Acta2 (assay MGI:6711822)
Structure Level Pattern Image Note
TS26: renal cortical interstitium Present 2P' Renal interstitium development is largely normal in the mutants even without nephron formation.
Specimen 2O'': embryonic day 18.5; Pax2tm1.1Akio/Pax2+, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: red - Tnc; green - Vim (assay MGI:6711820); blue - Acta2 (assay MGI:6711822)
Structure Level Pattern Image Note
TS26: inner medullary interstitium Present 2O'' Expression is seen in the interstitium adjacent to the pelvic urothelial lining.
Specimen 2P'': embryonic day 18.5; Pax2tm1.1Akio/Pax2tm1.2Akio, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: red - Tnc; green - Vim (assay MGI:6711820); blue - Acta2 (assay MGI:6711822)
Structure Level Pattern Image Note
TS26: inner medullary interstitium Present 2P'' Renal interstitium development is largely normal in the mutants even without nephron formation.
Specimen S2K: embryonic day 18.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pax2tm1.1Akio/Pax2+, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: red - Tnc; green - Vim (assay MGI:6711820); blue - Acta2 (assay MGI:6711822)
Structure Level Pattern Image Note
TS26: renal interstitium Present S2K
Specimen S2L: embryonic day 18.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pax2tm1.1Akio/Pax2tm1.2Akio, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: red - Tnc; green - Vim (assay MGI:6711820); blue - Acta2 (assay MGI:6711822)
Structure Level Pattern Image Note
TS26: renal interstitium Present S2L
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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