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Gene Expression Data
Assay Details
Assay
Reference: J:231231 Abby E, et al., Implementation of meiosis prophase I programme requires a conserved retinoid-independent stabilizer of meiotic transcripts. Nat Commun. 2016;7:10324
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6695333
Gene symbol: Stra8
Gene name: stimulated by retinoic acid gene 8
Results
Specimen 2a: postnatal day 8 (more )
Note: Double labeled: red - Stra8; green - Meioc (assay MGI:6695312).
Structure Level Pattern Image Note
TS28: spermatocyte Present Regionally restricted 2a middle , 2a top Expression was detected in premeiotic stage and leptotene stage.

Specimen 5d 8-dpp Meioc+/+: postnatal day 8 (more )
Note: Double labeled: green - Stra8; red - Sycp3 (assay MGI:6695313).
Structure Level Pattern Image Note
TS28: germ cell of testis Present 5d 8dpp Meioc+/+

Specimen 5d 8-dpp Meioc-/-: postnatal day 8; Meioctm1a(KOMP)Wtsi/Meioctm1a(KOMP)Wtsi (more )
Note: Double labeled: green - Stra8; red - Sycp3 (assay MGI:6695313).
Structure Level Pattern Image Note
TS28: germ cell of testis Present 5d 8dpp Meioc-/- Stra8 expression was relatively normal in the mutant at 8-dpp.

Specimen 5d 16-dpp Meioc+/+: postnatal day 16 (more )
Note: Double labeled: green - Stra8; red - Sycp3 (assay MGI:6695313).
Structure Level Pattern Image Note
TS28: germ cell of testis Ambiguous 5d 16dpp Meioc+/+

Specimen 5d 16-dpp Meioc-/-: postnatal day 16; Meioctm1a(KOMP)Wtsi/Meioctm1a(KOMP)Wtsi (more )
Note: Double labeled: green - Stra8; red - Sycp3 (assay MGI:6695313).
Structure Level Pattern Image Note
TS28: germ cell of testis Present 5d 16dpp Meioc-/- An abundance of cells still expressed Stra8 in the mutant.

Specimen 10d Stra8+/+: postnatal (more )
Note: Double labeled: green - Stra8; red - Meioc (assay MGI:6716028).
Structure Level Pattern Image Note
TS28: testis Present 10d Stra8+/+ right , 10d Stra8+/+ center

Specimen 10d Stra8-/-: postnatal; Stra8tm1.1Nbg/Stra8tm1.1Nbg (more )
Note: Double labeled: green - Stra8; red - Meioc (assay MGI:6716028).
Structure Level Pattern Image Note
TS28: testis Absent 10d Stra8-/- right , 10d Stra8-/- center


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory