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Gene Expression Data
Assay Details
Assay
Reference: J:296647 Wanner N, et al., DNA Methyltransferase 1 Controls Nephron Progenitor Cell Renewal and Differentiation. J Am Soc Nephrol. 2019 Jan;30(1):63-78
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6512080
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-activated Caspase 3 (AF835)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen S7B fl/fl: postnatal day 0-1; Dnmt1tm2Jae/Dnmt1tm2Jae (more )
Note: Double labeled: red - activated Casp3; green - Wt1 (assay MGI:6512074)
Structure Level Pattern Image Note
TS27: nephrogenic zone Trace Single cells S7b fl/fl Expression is seen in apoptotic cells, of which there are very few in either wild type or mutant.
Specimen S7B fl/fl; cre: postnatal day 0-1; Dnmt1tm2Jae/Dnmt1tm2Jae, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Double labeled: red - activated Casp3; green - Wt1 (assay MGI:6512074)
Structure Level Pattern Image Note
TS27: nephrogenic zone Trace Single cells S7b fl/fl; cre Expression is seen in apoptotic cells, of which there are very few in either wild type or mutant.
Specimen S7D: embryonic day 15.5; Dnmt1tm2Jae/Dnmt1tm2Jae, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Double labeled: red - activated Casp3; green - Wt1 (assay MGI:6512074)
Structure Level Pattern Image Note
TS23: renal cortex Trace Single cells S7d Expression is seen in apoptotic cells, of which there are very few in either wild type or mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/09/2025
MGI 6.24 		The Jackson Laboratory