About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:150043 Bush JO, et al., Ephrin-B1 regulates axon guidance by reverse signaling through a PDZ-dependent mechanism. Genes Dev. 2009 Jul 1;23(13):1586-99
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6500860
Gene symbol: Efnb1
Gene name: ephrin B1
Results
Specimen E13.5 not shown: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cerebral cortex Strong Widespread Strong expression throughout cortex between E13.5 and E18.5.
Specimen E18.5 not shown: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cerebral cortex Strong Widespread Strong expression throughout cortex between E13.5 and E18.5.
TS26: cerebral cortex intermediate zone Present Expression within ventricular and intermediate zones.
TS26: cerebral cortex ventricular layer Present Expression within ventricular and intermediate zones.
TS26: cerebral hemisphere white matter Present Regionally restricted Expression in radial glia.
Specimen 6C/D: embryonic day 18.0 (more )
Note: Triple labeled: red - Efnb1; green - L1cam (assay MGI:6500854); blue - Gfap (assay MGI:6500859).
Structure Level Pattern Image Note
TS26: corpus callosum Present Regionally restricted 6C , 6D Co-expression with L1cam in axons of corpus callosum.
TS26: indusium griseum Absent 6D , 6C No co-expression with Gfap in induseum griseum.
TS26: telencephalon pia mater Strong Regionally restricted 6D , 6C Strong expression within interhemispheric pial membrane cells.
Specimen 6G/H: embryonic day 18.0 (more )
Note: Triple labeled: red - Efnb1; green - L1cam (assay MGI:6500854); blue - Gfap (assay MGI:6500859).
Structure Level Pattern Image Note
TS26: telencephalon subventricular zone Present 6H , 6G
TS26: cerebral hemisphere white matter Present Regionally restricted 6H , 6G Expression in some but not all cells within glial wedge.
Specimen 6S/T: embryonic day 17.5; Efnb1tm3.2Sor/Efnb1tm3.2Sor (more )
Note: Triple labeled: red - Efnb1; green - L1cam (assay MGI:6500854); blue - Gfap (assay MGI:6500859).
Structure Level Pattern Image Note
TS25: telencephalon ventricular layer Present 6S , 6T Author report normal expression within ventricular zone.
TS25: corpus callosum Present Regionally restricted 6S , 6T Co-expression with L1cam within non-crossing corpus callosum axons.
TS25: indusium griseum Absent 6S , 6T No expression within mislocalized Gfap-expressing induseum griseum cells.
TS25: telencephalon pia mater Strong Regionally restricted 6T , 6S Strong expression within interhemispheric pial membrane cells.
Specimen S4B/C: embryonic day 16.5 (more )
Note: Double labeled: green - Efnb1; red - Gfap (assay MGI:6500859).
Structure Level Pattern Image Note
TS24: telencephalon subventricular zone Strong S4C , S4B Strongest expression within subventricular zone.
Specimen S4E/F: embryonic day 16.5 (more )
Note: Double labeled: green - Efnb1; red - Gfap (assay MGI:6500859).
Structure Level Pattern Image Note
TS24: corpus callosum Present S4F , S4E Expression also detectable within axons of corpus callosum.
Specimen S4H/I: embryonic day 16.5 (more )
Note: Double labeled: green - Efnb1; red - Gfap (assay MGI:6500859).
Structure Level Pattern Image Note
TS24: cerebral hemisphere white matter Present Regionally restricted S4H , S4I Expression within many cells of glial wedge.
Specimen S4K/L: embryonic day 16.5; Efnb1tm4.2Sor/Efnb1tm4.2Sor (more )
Note: Double labeled: green - Efnb1; red - Gfap (assay MGI:6500859).
Structure Level Pattern Image Note
TS24: cerebral hemisphere white matter Present Regionally restricted S4K , S4L Authors report expression is indistinguishable from wild type.
TS24: corpus callosum Present Regionally restricted S4K , S4L Authors report expression is indistinguishable from wild type.
TS24: telencephalon subventricular zone Present Regionally restricted S4K , S4L Authors report expression is indistinguishable from wild type.
Specimen S5B/D: embryonic day 17.5 (more )
Note: Triple labeled: blue - Efnb1; green - L1cam (assay MGI:6500854); red - Rgs3 (assay MGI:6500864).
Structure Level Pattern Image Note
TS25: corpus callosum Present S5B , S5D
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory