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Gene Expression Data
Assay Details
Assay
Reference: J:194894 Couesnon A, et al., CLIPR-59: a protein essential for neuromuscular junction stability during mouse late embryonic development. Development. 2013 Apr;140(7):1583-93
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6477284
Gene symbol: S100b
Gene name: S100 protein, beta polypeptide, neural
Antibody: anti-S-100
Results
Specimen 6Ba S-100: embryonic day 18.5; Clip3tm1.1Ics/Clip3+ (more )
Note: Triple labeled: red - S100b; green - alpha-Bungarotoxin; blue - Tubb3 (assay MGI:6477285).
Structure Level Pattern Image Note
TS26: diaphragm Present Regionally restricted 6Ba S-100 , 6Ba Merge Expression in Schwann cells capping neuromuscular junctions in both control and mutant diaphragm.
Specimen 6Bb S-100: embryonic day 18.5; Clip3tm1.1Ics/Clip3tm1.1Ics (more )
Note: Triple labeled: red - S100b; green - alpha-Bungarotoxin; blue - Tubb3 (assay MGI:6477285).
Structure Level Pattern Image Note
TS26: diaphragm Present Regionally restricted 6Bb S-100 , 6Bb Merge Expression in Schwann cells capping neuromuscular junctions in both control and mutant diaphragm.
Specimen 6Bc S-100: embryonic day 18.5; Clip3tm1.1Ics/Clip3+ (more )
Note: Triple labeled: red - S100b; green - alpha-Bungarotoxin; blue - Tubb3 (assay MGI:6477285).
Structure Level Pattern Image Note
TS26: diaphragm Present Regionally restricted 6Bc Merge , 6Bc S-100 Authors report normally shaped Schwann cells capping healthy neuromuscular junctions.
Specimen 6Bd S-100: embryonic day 18.5; Clip3tm1.1Ics/Clip3tm1.1Ics (more )
Note: Triple labeled: red - S100b; green - alpha-Bungarotoxin; blue - Tubb3 (assay MGI:6477285).
Structure Level Pattern Image Note
TS26: diaphragm Present Regionally restricted 6Bd Merge , 6Bd S-100 At tip of nerve branch, abnormally shaped Schwann cells observed next to shedding segments of disconnected axons.
Specimen S5Ba: embryonic day 18.5; Clip3tm1.1Ics/Clip3+ (more )
Note: Triple labeled: red - S100b; green - alpha-Bungarotoxin; blue - DAPI.
Structure Level Pattern Image Note
TS26: diaphragm Present Regionally restricted S5Ba Authors report similar Schwann cell extenstions in ventral part of diaphragm in both control and mutant.
Specimen S5Bb: embryonic day 18.5; Clip3tm1.1Ics/Clip3tm1.1Ics (more )
Note: Triple labeled: red - S100b; green - alpha-Bungarotoxin; blue - DAPI.
Structure Level Pattern Image Note
TS26: diaphragm Present Regionally restricted S5Bb Authors report similar Schwann cell extenstions in ventral part of diaphragm in both control and mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory