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Gene Expression Data
Assay Details
Assay
Reference: J:263986 De S, et al., Two distinct ontogenies confer heterogeneity to mouse brain microglia. Development. 2018 Jul 4;145(13):dev152306
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6473218
Gene symbol: Cx3cr1
Gene name: C-X3-C motif chemokine receptor 1
Reporter: GFP
Antibody: anti-GFP (Aves)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 1D: postnatal adult; Cx3cr1tm1Litt/Cx3cr1+, Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Hoxb8tm2.1(cre)Mrc/Hoxb8+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: frontal cortex Present 1D , 1F Expression is in parenchymal microglia.
Specimen E10.5: embryonic day 10.5; Cx3cr1tm1Litt/Cx3cr1+, Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Hoxb8tm2.1(cre)Mrc/Hoxb8+ (more )
Note: Conditional mutant. These data are shown as a graph in Figure 2A.
Structure Level Pattern Image Note
TS17: telencephalon Present Expression is in microglia.
Specimen E12.5: embryonic day 12.5; Cx3cr1tm1Litt/Cx3cr1+, Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Hoxb8tm2.1(cre)Mrc/Hoxb8+ (more )
Note: Conditional mutant. These data are shown as a graph in Figure 2A.
Structure Level Pattern Image Note
TS20: cerebral cortex Present Expression is in microglia.
Specimen E14.5: embryonic day 14.5; Cx3cr1tm1Litt/Cx3cr1+, Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Hoxb8tm2.1(cre)Mrc/Hoxb8+ (more )
Note: Conditional mutant. These data are shown as a graph in Figure 2A.
Structure Level Pattern Image Note
TS22: cerebral cortex Present Expression is in microglia.
Specimen E16.5: embryonic day 16.5; Cx3cr1tm1Litt/Cx3cr1+, Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Hoxb8tm2.1(cre)Mrc/Hoxb8+ (more )
Note: Conditional mutant. These data are shown as a graph in Figure 2A.
Structure Level Pattern Image Note
TS24: cerebral cortex Present Expression is in microglia.
Specimen E18.5: embryonic day 18.5; Cx3cr1tm1Litt/Cx3cr1+, Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Hoxb8tm2.1(cre)Mrc/Hoxb8+ (more )
Note: Conditional mutant. These data are shown as a graph in Figure 2A.
Structure Level Pattern Image Note
TS26: cerebral cortex Present Expression is in microglia.
Specimen P0: postnatal day 0; Cx3cr1tm1Litt/Cx3cr1+, Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Hoxb8tm2.1(cre)Mrc/Hoxb8+ (more )
Note: Conditional mutant. These data are shown as a graph in Figure 2A.
Structure Level Pattern Image Note
TS27: cerebral cortex Present Expression is in microglia.
Specimen P4: postnatal day 4; Cx3cr1tm1Litt/Cx3cr1+, Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Hoxb8tm2.1(cre)Mrc/Hoxb8+ (more )
Note: Conditional mutant. These data are shown as a graph in Figure 2A.
Structure Level Pattern Image Note
TS28: cerebral cortex Present Expression is in microglia.
Specimen P8: postnatal day 8; Cx3cr1tm1Litt/Cx3cr1+, Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Hoxb8tm2.1(cre)Mrc/Hoxb8+ (more )
Note: Conditional mutant. These data are shown as a graph in Figure 2A.
Structure Level Pattern Image Note
TS28: cerebral cortex Present Expression is in microglia.
Specimen P16: postnatal day 16; Cx3cr1tm1Litt/Cx3cr1+, Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Hoxb8tm2.1(cre)Mrc/Hoxb8+ (more )
Note: Conditional mutant. These data are shown as a graph in Figure 2A.
Structure Level Pattern Image Note
TS28: cerebral cortex Present Expression is in microglia.
Specimen 2B: embryonic day 10.5; Cx3cr1tm1Litt/Cx3cr1+, Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Hoxb8tm2.1(cre)Mrc/Hoxb8+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: telencephalon Present 2B Expression is in microglia.
Specimen 2C: embryonic day 12.5; Cx3cr1tm1Litt/Cx3cr1+, Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Hoxb8tm2.1(cre)Mrc/Hoxb8+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: cerebral cortex Present 2C Expression is in microglia.
Specimen 2D: embryonic day 14.5; Cx3cr1tm1Litt/Cx3cr1+, Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Hoxb8tm2.1(cre)Mrc/Hoxb8+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: cerebral cortex Present 2D
Specimen S3A: postnatal day 0; Cx3cr1tm1Litt/Cx3cr1+, Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Hoxb8tm2.1(cre)Mrc/Hoxb8+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: brain Present S3E , S3A , S3C Expression is in microglia.
Specimen S3F: postnatal day 4; Cx3cr1tm1Litt/Cx3cr1+, Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Hoxb8tm2.1(cre)Mrc/Hoxb8+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: brain Present S3J , S3F , S3H Expression is in microglia.
Specimen S3K: postnatal day 32; Cx3cr1tm1Litt/Cx3cr1+, Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Hoxb8tm2.1(cre)Mrc/Hoxb8+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: brain Present S3M , S3K , S3O Expression is in microglia.
Specimen S5: postnatal adult; Cx3cr1tm1Litt/Cx3cr1+, Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Hoxb8tm2.1(cre)Mrc/Hoxb8+ (more )
Note: Conditional mutant. Triple labeled: green - Cx3cr1 reporter; white - Tmem119 (assay MGI:6473205); red - Cre reporter.
Structure Level Pattern Image Note
TS28: brain Present S5_Cx3cr1-GFP , S5_merge Expression is in microglia.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/06/2026
MGI 6.24 		The Jackson Laboratory