About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:265020 Tang X, et al., EMC3 coordinates surfactant protein and lipid homeostasis required for respiration. J Clin Invest. 2017 Dec 1;127(12):4314-4325
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6456987
Gene symbol: Sftpb
Gene name: surfactant associated protein B
Results
Specimen 3A: embryonic day 18.5 (more )
Note: Double labeled: red - proSP-B (Sftpb); green - Abca3 (assay MGI:6456986).
Structure Level Pattern Image Note
TS26: lung Present 3A merge , 3A proSP-B
Specimen 3B: embryonic day 18.5; Emc3tm1c(EUCOMM)Wtsi/Emc3tm1c(EUCOMM)Wtsi, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant. Double labeled: red - proSP-B (Sftpb); green - Abca3 (assay MGI:6456986).
Structure Level Pattern Image Note
TS26: lung alveolus Strong Regionally restricted 3B proSP-B , 3B merge Expression accumulated in alveolar type 2 (AT2) cells. Abnormal expression in peripheral lung saccules.
Specimen 3E: embryonic day 18.5 (more )
Note: Triple labeled: green - proSP-B (Sftpbb); purple - proSP-C (Sftpc assay MGI:6456988); red - Lamp1 (assay MGI:6456990).
Structure Level Pattern Image Note
TS26: lung Present 3E
Specimen 3F: embryonic day 18.5; Emc3tm1c(EUCOMM)Wtsi/Emc3tm1c(EUCOMM)Wtsi, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant. Triple labeled: green - proSP-B (Sftpbb); purple - proSP-C (Sftpc assay MGI:6456988); red - Lamp1 (assay MGI:6456990).
Structure Level Pattern Image Note
TS26: lung alveolus Strong Regionally restricted 3F Expression colocalized with LAMP-1 in alveolar type 2 (AT2) cells, indicating retention of unprocessed precursors.
Specimen S2C: embryonic day 18.5 (more )
Note: Double labeled: green - proSP-B (Sftpbb); red - Ager (assay MGI:6456992).
Structure Level Pattern Image Note
TS26: lung Present S2C merge , S2C proSP-B
Specimen S2D: embryonic day 18.5; Emc3tm1c(EUCOMM)Wtsi/Emc3tm1c(EUCOMM)Wtsi, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant. Double labeled: green - proSP-B (Sftpbb); red - Ager (assay MGI:6456992).
Structure Level Pattern Image Note
TS26: lung Present S2D merge , S2D pro-SP-B
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory