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Gene Expression Data
Assay Details
Assay
Reference: J:198547 Neves G, et al., The LIM Homeodomain Protein Lhx6 Regulates Maturation of Interneurons and Network Excitability in the Mammalian Cortex. Cereb Cortex. 2013 Aug;23(8):1811-23
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6443621
Gene symbol: Npy
Gene name: neuropeptide Y
Antibody: Anti-Npy (T-4069)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 5C: postnatal week 4; Lhx6tm1Vpa/Lhx6+ (more )
Note: Double labeled: green - Npy; red - Sst (assay MGI:6443607).
Structure Level Pattern Image Note
TS28: dentate gyrus hilus Present Regionally restricted 5C Expression is in interneurons.

Specimen 5D: postnatal week 4; Lhx6tm1Vpa/Lhx6+ (more )
Note: Double labeled: green - Npy; red - Sst (assay MGI:6443607).
Structure Level Pattern Image Note
TS28: dentate gyrus hilus Present Regionally restricted 5D Expression is in interneurons.

Specimen 5E: postnatal week 4; Lhx6tm1Vpa/Lhx6tm2Vpa (more )
Note: Double labeled: green - Npy; red - Sst (assay MGI:6443607).
Structure Level Pattern Image Note
TS28: dentate gyrus hilus Present Regionally restricted 5E The number of Npy positive interneurons was similar to controls.

Specimen 5F: postnatal week 4; Lhx6tm1Vpa/Lhx6tm2Vpa (more )
Note: Double labeled: green - Npy; red - Sst (assay MGI:6443607).
Structure Level Pattern Image Note
TS28: dentate gyrus hilus Present Regionally restricted 5F The number of Npy positive interneurons was similar to controls.

Specimen 7E: postnatal week 4; Lhx6tm1Vpa/Lhx6tm2Vpa (more )
Structure Level Pattern Image Note
TS28: dentate gyrus granule cell layer Absent 7E 88% lacked staining in the mossy fibers.

Specimen 7F: postnatal week 8; Lhx6tm1Vpa/Lhx6tm2Vpa (more )
Structure Level Pattern Image Note
TS28: dentate gyrus granule cell layer Very strong Regionally restricted 7F Expression is in mossy fibers.

Specimen not shown Pw4: postnatal week 4; Lhx6tm1Vpa/Lhx6+ (more )
Structure Level Pattern Image Note
TS28: dentate gyrus granule cell layer Absent 88% lacked staining in the mossy fibers.

Specimen not shown Pw8: postnatal week 8; Lhx6tm1Vpa/Lhx6+ (more )
Structure Level Pattern Image Note
TS28: dentate gyrus granule cell layer Absent


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory