Gene Expression Data
Assay Details
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Assay
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Reference:
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J:198547
Neves G, et al., The LIM Homeodomain Protein Lhx6 Regulates Maturation of Interneurons and Network Excitability in the Mammalian Cortex. Cereb Cortex. 2013 Aug;23(8):1811-23
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:6443607
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Gene symbol:
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Sst
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Gene name:
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somatostatin
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Antibody:
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anti-Sst
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Detection system:
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Secondary antibody coupled to Alexa Fluor 568
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Results
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Specimen
4L:
postnatal week 4; Lhx6tm1Vpa/Lhx6 +
(more  )
Specimen
4L:
(close  )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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Lhx6tm1Vpa/Lhx6+
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Age:
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postnatal week 4
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
4M:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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Lhx6tm1Vpa/Lhx6tm2Vpa
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Age:
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postnatal week 4
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: dentate gyrus |
Present |
Regionally restricted |
4M
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The number of positive interneurons was reduced in this mutant to about 30% compared to controls.
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| TS28: hippocampus CA1 |
Present |
Regionally restricted |
4M
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The number of positive interneurons was reduced in this mutant to about 30% compared to controls.
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Specimen
5A:
postnatal week 4; Lhx6tm1Vpa/Lhx6 +
(more )
Note: Double labeled: red - Sst; green - Calb2 (assay MGI:6443614).
Specimen
5A:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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Lhx6tm1Vpa/Lhx6+
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Age:
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postnatal week 4
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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Double labeled: red - Sst; green - Calb2 (assay MGI:6443614).
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Specimen
5B:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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Lhx6tm1Vpa/Lhx6tm2Vpa
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Age:
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postnatal week 4
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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Double labeled: red - Sst; green - Calb2 (assay MGI:6443614).
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: cerebral cortex |
Present |
Regionally restricted |
5B
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The number of positive interneurons was reduced in this mutant compared to controls.
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Specimen
5C:
postnatal week 4; Lhx6tm1Vpa/Lhx6 +
(more )
Note: Double labeled: red - Sst; green - Npy (assay MGI:6443621).
Specimen
5C:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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Lhx6tm1Vpa/Lhx6+
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Age:
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postnatal week 4
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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Double labeled: red - Sst; green - Npy (assay MGI:6443621).
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Specimen
5D:
postnatal week 4; Lhx6tm1Vpa/Lhx6 +
(more )
Note: Double labeled: red - Sst; green - Npy (assay MGI:6443621).
Specimen
5D:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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Lhx6tm1Vpa/Lhx6+
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Age:
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postnatal week 4
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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Double labeled: red - Sst; green - Npy (assay MGI:6443621).
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Specimen
5E:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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Lhx6tm1Vpa/Lhx6tm2Vpa
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Age:
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postnatal week 4
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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Double labeled: red - Sst; green - Npy (assay MGI:6443621).
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: dentate gyrus hilus |
Present |
Regionally restricted |
5E
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The number of positive interneurons was reduced in this mutant compared to controls.
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Specimen
5F:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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Lhx6tm1Vpa/Lhx6tm2Vpa
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Age:
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postnatal week 4
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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Double labeled: red - Sst; green - Npy (assay MGI:6443621).
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: dentate gyrus hilus |
Present |
Regionally restricted |
5F
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The number of positive interneurons was reduced in this mutant compared to controls.
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Specimen
5G:
postnatal week 4; Lhx6tm1Vpa/Lhx6 +
(more )
Note: Double labeled: red - Sst; green - Gria1 (assay MGI:6443623).
Specimen
5G:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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Lhx6tm1Vpa/Lhx6+
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Age:
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postnatal week 4
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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Double labeled: red - Sst; green - Gria1 (assay MGI:6443623).
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Specimen
5H:
postnatal week 4; Lhx6tm1Vpa/Lhx6 +
(more )
Note: Double labeled: red - Sst; green - Gria1 (assay MGI:6443623).
Specimen
5H:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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Lhx6tm1Vpa/Lhx6+
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Age:
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postnatal week 4
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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Double labeled: red - Sst; green - Gria1 (assay MGI:6443623).
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Specimen
5I:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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Lhx6tm1Vpa/Lhx6tm2Vpa
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Age:
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postnatal week 4
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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Double labeled: red - Sst; green - Gria1 (assay MGI:6443623).
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: hippocampus CA1 |
Present |
Regionally restricted |
5I
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The number of positive interneurons was reduced in this mutant compared to controls.
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| TS28: hippocampus CA3 |
Present |
Regionally restricted |
5I
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The number of positive interneurons was reduced in this mutant compared to controls.
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| TS28: hippocampus stratum oriens |
Present |
Regionally restricted |
5I
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The number of positive interneurons was reduced in this mutant compared to controls.
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Specimen
5J:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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Lhx6tm1Vpa/Lhx6tm2Vpa
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Age:
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postnatal week 4
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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|
Embedding:
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Cryosection
|
|
Note:
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Double labeled: red - Sst; green - Gria1 (assay MGI:6443623).
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: hippocampus CA1 |
Present |
Regionally restricted |
5J
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The number of positive interneurons was reduced in this mutant compared to controls.
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| TS28: hippocampus CA3 |
Present |
Regionally restricted |
5J
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The number of positive interneurons was reduced in this mutant compared to controls.
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| TS28: hippocampus stratum oriens |
Present |
Regionally restricted |
5J
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The number of positive interneurons was reduced in this mutant compared to controls.
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Analysis Tools