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Gene Expression Data
Assay Details
Assay
Reference: J:198547 Neves G, et al., The LIM Homeodomain Protein Lhx6 Regulates Maturation of Interneurons and Network Excitability in the Mammalian Cortex. Cereb Cortex. 2013 Aug;23(8):1811-23
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6443607
Gene symbol: Sst
Gene name: somatostatin
Antibody: anti-Sst
Detection system: Secondary antibody coupled to Alexa Fluor 568
Results
Specimen 4L: postnatal week 4; Lhx6tm1Vpa/Lhx6+ (more )
Structure Level Pattern Image Note
TS28: dentate gyrus Present Regionally restricted 4L Expression in in interneurons.
TS28: hippocampus CA1 Present Regionally restricted 4L Expression in in interneurons.
Specimen 4M: postnatal week 4; Lhx6tm1Vpa/Lhx6tm2Vpa (more )
Structure Level Pattern Image Note
TS28: dentate gyrus Present Regionally restricted 4M The number of positive interneurons was reduced in this mutant to about 30% compared to controls.
TS28: hippocampus CA1 Present Regionally restricted 4M The number of positive interneurons was reduced in this mutant to about 30% compared to controls.
Specimen 5A: postnatal week 4; Lhx6tm1Vpa/Lhx6+ (more )
Note: Double labeled: red - Sst; green - Calb2 (assay MGI:6443614).
Structure Level Pattern Image Note
TS28: cerebral cortex Present Regionally restricted 5A
Specimen 5B: postnatal week 4; Lhx6tm1Vpa/Lhx6tm2Vpa (more )
Note: Double labeled: red - Sst; green - Calb2 (assay MGI:6443614).
Structure Level Pattern Image Note
TS28: cerebral cortex Present Regionally restricted 5B The number of positive interneurons was reduced in this mutant compared to controls.
Specimen 5C: postnatal week 4; Lhx6tm1Vpa/Lhx6+ (more )
Note: Double labeled: red - Sst; green - Npy (assay MGI:6443621).
Structure Level Pattern Image Note
TS28: dentate gyrus hilus Present Regionally restricted 5C Expression in in interneurons.
Specimen 5D: postnatal week 4; Lhx6tm1Vpa/Lhx6+ (more )
Note: Double labeled: red - Sst; green - Npy (assay MGI:6443621).
Structure Level Pattern Image Note
TS28: dentate gyrus hilus Present Regionally restricted 5D Expression in in interneurons.
Specimen 5E: postnatal week 4; Lhx6tm1Vpa/Lhx6tm2Vpa (more )
Note: Double labeled: red - Sst; green - Npy (assay MGI:6443621).
Structure Level Pattern Image Note
TS28: dentate gyrus hilus Present Regionally restricted 5E The number of positive interneurons was reduced in this mutant compared to controls.
Specimen 5F: postnatal week 4; Lhx6tm1Vpa/Lhx6tm2Vpa (more )
Note: Double labeled: red - Sst; green - Npy (assay MGI:6443621).
Structure Level Pattern Image Note
TS28: dentate gyrus hilus Present Regionally restricted 5F The number of positive interneurons was reduced in this mutant compared to controls.
Specimen 5G: postnatal week 4; Lhx6tm1Vpa/Lhx6+ (more )
Note: Double labeled: red - Sst; green - Gria1 (assay MGI:6443623).
Structure Level Pattern Image Note
TS28: hippocampus CA1 Present Regionally restricted 5G Expression in in interneurons.
TS28: hippocampus CA3 Present Regionally restricted 5G Expression in in interneurons.
TS28: hippocampus stratum oriens Present Regionally restricted 5G Expression in in interneurons.
Specimen 5H: postnatal week 4; Lhx6tm1Vpa/Lhx6+ (more )
Note: Double labeled: red - Sst; green - Gria1 (assay MGI:6443623).
Structure Level Pattern Image Note
TS28: hippocampus CA1 Present Regionally restricted 5H Expression in in interneurons.
TS28: hippocampus CA3 Present Regionally restricted 5H Expression in in interneurons.
TS28: hippocampus stratum oriens Present Regionally restricted 5H Expression in in interneurons.
Specimen 5I: postnatal week 4; Lhx6tm1Vpa/Lhx6tm2Vpa (more )
Note: Double labeled: red - Sst; green - Gria1 (assay MGI:6443623).
Structure Level Pattern Image Note
TS28: hippocampus CA1 Present Regionally restricted 5I The number of positive interneurons was reduced in this mutant compared to controls.
TS28: hippocampus CA3 Present Regionally restricted 5I The number of positive interneurons was reduced in this mutant compared to controls.
TS28: hippocampus stratum oriens Present Regionally restricted 5I The number of positive interneurons was reduced in this mutant compared to controls.
Specimen 5J: postnatal week 4; Lhx6tm1Vpa/Lhx6tm2Vpa (more )
Note: Double labeled: red - Sst; green - Gria1 (assay MGI:6443623).
Structure Level Pattern Image Note
TS28: hippocampus CA1 Present Regionally restricted 5J The number of positive interneurons was reduced in this mutant compared to controls.
TS28: hippocampus CA3 Present Regionally restricted 5J The number of positive interneurons was reduced in this mutant compared to controls.
TS28: hippocampus stratum oriens Present Regionally restricted 5J The number of positive interneurons was reduced in this mutant compared to controls.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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