About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:229352 Metzger DE, et al., Grg3/TLE3 and Grg1/TLE1 induce monohormonal pancreatic beta-cells while repressing alpha-cell functions. Diabetes. 2014 May;63(5):1804-16
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6441183
Gene symbol: Gcg
Gene name: glucagon
Antibody: anti-glucagon
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen S2A: embryonic day 14.5 (more )
Note: Triple labeled: red - Gcg; gray - Pdx1 (assay MGI:6441184); green - Ins1 (assay MGI:6441182) and Ins2 (assay MGI:6441476).
Structure Level Pattern Image Note
TS22: pancreas Present S2A Expressed in alpha-cells. Not coexpressed with Insulin.
Specimen S2B: embryonic day 14.5; Tle3tm1Jcc/Tle3+ (more )
Note: Triple labeled: red - Gcg; gray - Pdx1 (assay MGI:6441184); green - Ins1 (assay MGI:6441182) and Ins2 (assay MGI:6441476).
Structure Level Pattern Image Note
TS22: pancreas Present S2B A few endocrine cells were bihormonal (coexpressed Insulin and Gcg).
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/21/2024
MGI 6.23 		The Jackson Laboratory