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Gene Expression Data
Assay Details
Assay
Reference: J:222345 Rogers SW, et al., Nicotinic receptor Alpha7 expression during tooth morphogenesis reveals functional pleiotropy. PLoS One. 2012;7(5):e36467
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6433099
Gene symbol: Edar
Gene name: ectodysplasin-A receptor
Antibody: anti-EDAR
Detection system: Secondary antibody
Results
Specimen 3A: embryonic day 14.5; Chrna7tm1.1Swr/Chrna7+ (more )
Note: Double labeled: red - Edar; green - Chrna7 (assay MGI:6433065).
Structure Level Pattern Image Note
TS22: primary enamel knot Present 3A EDER , 3A Merge
TS22: molar dental papilla Present Scattered 3A Merge , 3A EDER Coexpressed with Chrna7 in scattered cells in the dental papilla surrounding the mesenchyme. The majority of these cells have a classic spider-like morphology characteristic of macrophages.

Specimen 3B: embryonic day 16.5; Chrna7tm1.1Swr/Chrna7+ (more )
Note: Double labeled: red - Edar; green - Chrna7 (assay MGI:6433065).
Structure Level Pattern Image Note
TS24: secondary enamel knot Present 3B Merge , 3B EDAR

Specimen not shown: embryonic day 13.5; Chrna7tm1.1Swr/Chrna7+ (more )
Note: Also stained for Chrna7 (assay MGI:6433065).
Structure Level Pattern Image Note
TS21: primary enamel knot Present

Specimen not shown: embryonic day 15.5; Chrna7tm1.1Swr/Chrna7+ (more )
Note: Also stained for Chrna7 (assay MGI:6433065).
Structure Level Pattern Image Note
TS23: primary enamel knot Present


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory