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Gene Expression Data
Assay Details
Assay
Reference: J:237528 Lilly AJ, et al., Interplay between SOX7 and RUNX1 regulates hemogenic endothelial fate in the yolk sac. Development. 2016 Dec 01;143(23):4341-4351
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6392025
Gene symbol: Sox7
Gene name: SRY (sex determining region Y)-box 7
Antibody: Human SOX7 Antibody
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 2B: embryonic day 8.5 (more )
Note: Double labeled: green - Sox7; purple - Runx1 (assay MGI:6392035), Runx2 (assay MGI:6392095) and Runx3 (assay MGI:6392096).
Structure Level Pattern Image Note
TS13: blood island Present Regionally restricted 2B Sox7 , 2B Merge Expressed in endothelial cells on the edges of blood island regions.

Specimen 2C: embryonic day 8.5 (more )
Note: Triple labeled: green - Sox7; white - Pecam1 (assay MGI:6392036); purple - Runx1 (assay MGI:6392035), Runx2 (assay MGI:6392095) and Runx3 (assay MGI:6392096).
Structure Level Pattern Image Note
TS13: blood island Present Regionally restricted 2C Merge , 2C Sox7 Expressed in endothelial cells on the edges of blood island regions.

Specimen 2D: embryonic day 9.5 (more )
Note: Triple labeled: green - Sox7; white - Pecam1 (assay MGI:6392036); purple - Runx1 (assay MGI:6392035), Runx2 (assay MGI:6392095) and Runx3 (assay MGI:6392096).
Structure Level Pattern Image Note
TS15: yolk sac blood vessel Present 2D Merge , 2D Sox7 More Runx-coexpressing endothelial cells.

Specimen 2E: embryonic day 9.5 (more )
Note: Triple labeled: green - Sox7; white - Pecam1 (assay MGI:6392036); purple - Runx1 (assay MGI:6392035), Runx2 (assay MGI:6392095) and Runx3 (assay MGI:6392096).
Structure Level Pattern Image Note
TS15: dorsal aorta Present Regionally restricted 2E Merge , 2E Sox7 Coexpressed with Runx in endothelial cells.

Specimen S2B: embryonic day 8.5 (more )
Note: Triple labeled: green - Sox7; white - Pecam1 (assay MGI:6392036); purple - Runx1 (assay MGI:6392035), Runx2 (assay MGI:6392095) and Runx3 (assay MGI:6392096).
Structure Level Pattern Image Note
TS13: blood island Present Regionally restricted S2B Sox7 , S2B Merge Expressed in endothelial cells on the edges of blood island regions.

Specimen S2C: embryonic day 9.5 (more )
Note: Triple labeled: green - Sox7; white - Pecam1 (assay MGI:6392036); purple - Runx1 (assay MGI:6392035), Runx2 (assay MGI:6392095) and Runx3 (assay MGI:6392096).
Structure Level Pattern Image Note
TS15: yolk sac Present Widespread S2C Sox7 , S2C Merge Expressed throughout the yolk sac. Higher expression in endothelial cells of the larger blood vessels.
TS15: yolk sac blood vessel Present Widespread S2C Sox7 , S2C Merge Higher expression in endothelial cells of the larger blood vessels.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory