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Gene Expression Data
Assay Details
Assay
Reference: J:228519 Jia S, et al., Insm1 controls the differentiation of pulmonary neuroendocrine cells by repressing Hes1. Dev Biol. 2015 Dec 1;408(1):90-8
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6391191
Gene symbol: Uchl1
Gene name: ubiquitin carboxy-terminal hydrolase L1
Antibody: anti-Pgp9.5 (Ab5898)
Assay notes: Two antibodies were described, but the one used in this assay was not detailed. Anti-Pgp9.5 MGI6391182 may have been used in this assay.
Results
Specimen 1A E13.5: embryonic day 13.5; Insm1tm1Cbm/Insm1+ (more )
Note: Double labeled: green - Pgp9.5 (Uchl1); red - Insm1 (assay MGI:6391190).
Structure Level Pattern Image Note
TS21: lung epithelium Absent 1A E13.5
Specimen 1A E14.5: embryonic day 14.5; Insm1tm1Cbm/Insm1+ (more )
Note: Double labeled: green - Pgp9.5 (Uchl1); red - Insm1 (assay MGI:6391190).
Structure Level Pattern Image Note
TS22: lung epithelium Present 1A E14.5 Expression beginning at E14.5.
Specimen 1B +/lacZ (upper): embryonic day 18.5; Insm1tm1Cbm/Insm1+ (more )
Note: Double labeled: green - Pgp9.5 (Uchl1); red - Insm1 reporter (assay MGI:6391189).
Structure Level Pattern Image Note
TS26: lung epithelium Present Regionally restricted 1B +/lacZ (upper) Expression in neuroendocrine cells of distal lung.
Specimen 1B lacZ/lacZ (upper): embryonic day 18.5; Insm1tm1Cbm/Insm1tm1Cbm (more )
Note: Double labeled: green - Pgp9.5 (Uchl1); red - Insm1 reporter (assay MGI:6391189).
Structure Level Pattern Image Note
TS26: lung epithelium Absent 1B lacZ/lacZ (upper)
Specimen 1C +/lacZ (upper): embryonic day 18.5; Insm1tm1Cbm/Insm1+ (more )
Note: Double labeled: green - Pgp9.5 (Uchl1); red - Insm1 reporter (assay MGI:6391189).
Structure Level Pattern Image Note
TS26: lung epithelium Present 1C +/lacZ (upper) Expression in neuroendocrine cells of proximal lung.
Specimen 1C lacZ/lacZ (upper): embryonic day 18.5; Insm1tm1Cbm/Insm1tm1Cbm (more )
Note: Double labeled: green - Pgp9.5 (Uchl1); red - Insm1 reporter (assay MGI:6391189).
Structure Level Pattern Image Note
TS26: lung epithelium Absent 1C lacZ/lacZ (upper)
Specimen 2A +/lacZ: embryonic day 14.5; Insm1tm1Cbm/Insm1+ (more )
Note: Double labeled: green - Pgp9.5 (Uchl1); red - Insm1 reporter (assay MGI:6391189).
Structure Level Pattern Image Note
TS22: lung epithelium Present 2A +/lacZ (left) , 2A +/lacZ (right)
Specimen 2A lacZ/lacZ: embryonic day 14.5; Insm1tm1Cbm/Insm1tm1Cbm (more )
Note: Double labeled: green - Pgp9.5 (Uchl1); red - Insm1 reporter (assay MGI:6391189).
Structure Level Pattern Image Note
TS22: lung epithelium Weak 2A lacZ/lacZ (left) , 2A lacZ/lacZ (right)
Specimen 2B +/lacZ: embryonic day 16.5; Insm1tm1Cbm/Insm1+ (more )
Note: Double labeled: green - Pgp9.5 (Uchl1); red - Insm1 reporter (assay MGI:6391189).
Structure Level Pattern Image Note
TS24: lung epithelium Present 2B +//lacZ (left) , 2B +/lacZ (right)
Specimen 2B lacZ/lacZ: embryonic day 16.5; Insm1tm1Cbm/Insm1tm1Cbm (more )
Note: Double labeled: green - Pgp9.5 (Uchl1); red - Insm1 reporter (assay MGI:6391189).
Structure Level Pattern Image Note
TS24: lung epithelium Absent 2B lacZ/lacZ (right)
Specimen 2C +/lacZ: embryonic day 18.5; Insm1tm1Cbm/Insm1+ (more )
Note: Double labeled: green - Pgp9.5 (Uchl1); red - Insm1 reporter (assay MGI:6391189).
Structure Level Pattern Image Note
TS26: lung epithelium Present 2C +/lacZ (right) , 2C +/lacZ (left)
Specimen 2C lacZ/lacZ: embryonic day 18.5; Insm1tm1Cbm/Insm1tm1Cbm (more )
Note: Double labeled: green - Pgp9.5 (Uchl1); red - Insm1 reporter (assay MGI:6391189).
Structure Level Pattern Image Note
TS26: lung epithelium Absent 2C lacZ/lacZ (right)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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