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Gene Expression Data
Assay Details
Assay
Reference: J:231098 Theveniau-Ruissy M, et al., Coronary stem development in wild-type and Tbx1 null mouse hearts. Dev Dyn. 2016 Apr;245(4):445-59
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6389811
Gene symbol: Pecam1
Gene name: platelet/endothelial cell adhesion molecule 1
Antibody: anti-CD31
Detection system: Secondary antibody
Results
Specimen 2A upper left: embryonic day 11.5; Gja5tm1Lumi/Gja5+ (more )
Note: Double labeled: red - Pecam1; green - Gja5 reporter (assay MGI:6389791).
Structure Level Pattern Image Note
TS19: ascending aorta Present Regionally restricted 2A upper left Coexpressed with Gja5 in the aortic endothelium and the future right and left ostia positions.
TS19: outflow tract distal part Present Regionally restricted 2A upper left Expressed in the distal arterial mesenchymal wall.

Specimen 2A upper middle: embryonic day 11.5; Gja5tm1Lumi/Gja5+ (more )
Note: Double labeled: red - Pecam1; green - Gja5 reporter (assay MGI:6389791).
Structure Level Pattern Image Note
TS19: ascending aorta Present Regionally restricted 2A upper middle Coexpressed with Gja5 in the aortic endothelium and future right and left ostia positions.
TS19: outflow tract distal part Present 2A upper middle

Specimen 2A upper right: embryonic day 11.5; Gja5tm1Lumi/Gja5+ (more )
Note: Double labeled: red - Pecam1; green - Gja5 reporter (assay MGI:6389791).
Structure Level Pattern Image Note
TS19: ascending aorta Present Regionally restricted 2A upper right Expressed in the endothelium.

Specimen 2B upper left: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: ascending aorta Present Regionally restricted 2B upper left Expressed in the sinusoids, aorta and future ostia. Clusters of endothelial cells were observed in the distal but not proximal aortic wall.

Specimen 2B upper middle upper: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: ascending aorta Present 2B upper middle upper Expressed in the aorta and future ostia.

Specimen 2B upper middle lower: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: ascending aorta Present 2B upper middle lower Expressed in the aorta and future ostia.

Specimen 2B upper right: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: ascending aorta Present Regionally restricted 2B upper right Expressed in the endothelium. No endothelial cells were observed in myocardium adjacent to the cardiac cushions.

Specimen 4B left: embryonic day 12.5; Gja5tm1Lumi/Gja5+, Tbx1tm1Pa/Tbx1tm1Pa (more )
Note: Double labeled: red - Pecam1; green - Gja5 reporter (assay MGI:6389791).
Structure Level Pattern Image Note
TS20: ascending aorta Present 4B left Expressed in common arterial trunk endothelium, coronary ostia and periarterial plexus cells.
TS20: coronary vascular plexus Present 4B left

Specimen 4B right: embryonic day 12.5; Gja5tm1Lumi/Gja5+, Tbx1tm1Pa/Tbx1tm1Pa (more )
Note: Double labeled: red - Pecam1; green - Gja5 reporter (assay MGI:6389791).
Structure Level Pattern Image Note
TS20: ascending aorta Present 4B right Expressed in common arterial trunk endothelium, coronary ostia and periarterial plexus cells.
TS20: coronary vascular plexus Present 4B right


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory