About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:136720 Friedrichs M, et al., Lamination of the cerebral cortex is disturbed in Gli3 mutant mice. Dev Biol. 2008 Jun 1;318(1):203-14
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6383090
Gene symbol: Nes
Gene name: nestin
Antibody: clone RC2
Results
Specimen 7C: embryonic day 14.5 (more )
Note: Double labeled: red - Nes; green - Reln (assay MGI:6383088).
Structure Level Pattern Image Note
TS22: cerebral cortex Present Regionally restricted 7C Expression is in radial glial cells in fibers that extend from the ventricular to the pial cortical surface.
Specimen 7G: embryonic day 14.5; Gli3Pdn/Gli3Xt-J (more )
Note: Double labeled: red - Nes; green - Reln (assay MGI:6383088).
Structure Level Pattern Image Note
TS22: cerebral cortex Present Regionally restricted 7G Expression is in the radial glial scaffold which is disrupted and shortened in this mutant.
Specimen 7K: embryonic day 14.5 (more )
Note: Double labeled: red - Nes; green - Calb1 (assay MGI:6383059).
Structure Level Pattern Image Note
TS22: cerebral cortex Present Regionally restricted 7K Expression is in radial glial cells in fibers that extend from the ventricular to the pial cortical surface.
Specimen 7N: embryonic day 14.5; Gli3Pdn/Gli3Xt-J (more )
Note: Double labeled: red - Nes; green - Calb1 (assay MGI:6383059).
Structure Level Pattern Image Note
TS22: cerebral cortex Present Regionally restricted 7N Expression is in the radial glial scaffold which is disrupted and shortened in this mutant.
Specimen 8A: postnatal day 0 (more )
Note: Double labeled: red - Nes; green - Tbr1 (assay MGI:6383071).
Structure Level Pattern Image Note
TS27: cerebral cortex Present Regionally restricted 8A , 8C Expression is in the radial glial scaffold.
Specimen 8D: postnatal day 0; Gli3Pdn/Gli3Xt-J (more )
Note: Double labeled: red - Nes; green - Tbr1 (assay MGI:6383071).
Structure Level Pattern Image Note
TS27: cerebral cortex Present Regionally restricted 8F , 8D There is a disorganization of the glial scaffold in this mutant.
Specimen 8G: postnatal day 0; Gli3Pdn/Gli3Xt-J (more )
Note: Double labeled: red - Nes; green - Tbr1 (assay MGI:6383071).
Structure Level Pattern Image Note
TS27: cerebral cortex Present Regionally restricted 8G , 8I There is a disorganization of the glial scaffold in this mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory