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Gene Expression Data
Assay Details
Assay
Reference: J:132598 Nishimura W, et al., Preferential reduction of beta cells derived from Pax6-MafB pathway in MafB deficient mice. Dev Biol. 2008 Feb 15;314(2):443-56
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6382869
Gene symbol: Nkx2-2
Gene name: NK2 homeobox 2
Antibody: 74.5A5
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to Alexa Fluor 488
Results
Specimen S1C: embryonic day 15.5 (more )
Note: Double labeled: green - Nkx2-2; red - Ins1 (assay MGI:6382865) and Ins2 (assay MGI:6382879).
Structure Level Pattern Image Note
TS23: pancreas Present S1C

Specimen S1H: embryonic day 15.5; Pax6Sey-Neu/Pax6+ (more )
Note: Double labeled: green - Nkx2-2; red - Ins1 (assay MGI:6382865) and Ins2 (assay MGI:6382879).
Structure Level Pattern Image Note
TS23: pancreas Present S1H Authors report normal expression.

Specimen 6B: embryonic day 15.5 (more )
Note: Double labeled: green - Nkx2-2; red - Ins1 (assay MGI:6382865) and Ins2 (assay MGI:6382879).
Structure Level Pattern Image Note
TS23: pancreas Present 6B

Specimen 6E: embryonic day 15.5; Mafbm1Gsb/Mafbm1Gsb (more )
Note: Double labeled: green - Nkx2-2; red - Ins1 (assay MGI:6382865) and Ins2 (assay MGI:6382879).
Structure Level Pattern Image Note
TS23: pancreas Present 6E Number of expressing cells not affected compared with wild type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory