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Gene Expression Data
Assay Details
Assay
Reference: J:174215 Chen Y, et al., Plasticity of neural crest-placode interaction in the developing visceral nervous system. Dev Dyn. 2011 Aug;240(8):1880-8
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6381627
Gene symbol: Isl1
Gene name: ISL1 transcription factor, LIM/homeodomain
Antibody: anti-Isl1/2
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 2A: embryonic day 10.5 (more )
Note: Double labeled: green - Isl1; red - Phox2b (assay MGI:6381438).
Structure Level Pattern Image Note
TS17: facial ganglion Present 2A
TS17: facio-acoustic ganglion complex Present 2A
TS17: trigeminal ganglion Present 2A
Specimen 2B: embryonic day 10.5; Hoxa1tm3.1Mrc/Hoxa1tm3.1Mrc, Hoxb1tm3Mrc/Hoxb1tm3Mrc (more )
Note: Double labeled: green - Isl1; red - Phox2b (assay MGI:6381438).
Structure Level Pattern Image Note
TS17: facial ganglion Present 2B The ganglia are fused in this mutant.
TS17: facio-acoustic ganglion complex Present 2B The ganglia are fused in this mutant.
TS17: trigeminal ganglion Present 2B The ganglia are fused in this mutant.
Specimen 2C: embryonic day 9.5 (more )
Note: Double labeled: green - Isl1; red - Phox2b (assay MGI:6381438).
Structure Level Pattern Image Note
TS15: facio-acoustic preganglion complex Present 2C
TS15: trigeminal preganglion Present 2C
Specimen 2D: embryonic day 9.5; Hoxa1tm3.1Mrc/Hoxa1tm3.1Mrc, Hoxb1tm3Mrc/Hoxb1tm3Mrc (more )
Note: Double labeled: green - Isl1; red - Phox2b (assay MGI:6381438).
Structure Level Pattern Image Note
TS15: facio-acoustic preganglion complex Present 2D Ganglia are fused in this mutant.
TS15: trigeminal preganglion Present 2D Ganglia are fused in this mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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