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Gene Expression Data
Assay Details
Assay
Reference: J:122556 Inoue T, et al., Zic2 and Zic3 synergistically control neurulation and segmentation of paraxial mesoderm in mouse embryo. Dev Biol. 2007 Jun 15;306(2):669-84
Assay type: RNA in situ
MGI Accession ID: MGI:6377220
Gene symbol: T
Gene name: brachyury, T-box transcription factor T
Probe: T probe36
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 7A: embryonic day 8.5 (more )
Note: Also stained for Uncx (assay MGI:6377213) and Otx2 (assay MGI:6377223).
Structure Level Pattern Image Note
TS13: unsegmented mesenchyme Present 7A
Specimen 7B: embryonic day 8.5; Zic3Bn/Y (more )
Note: Also stained for Uncx (assay MGI:6377213) and Otx2 (assay MGI:6377223).
Structure Level Pattern Image Note
TS13: unsegmented mesenchyme Present 7B
Specimen 7C: embryonic day 8.5; Zic2tm1Jaru/Zic2+, Zic3Bn/Y (more )
Note: Also stained for Uncx (assay MGI:6377213) and Otx2 (assay MGI:6377223).
Structure Level Pattern Image Note
TS13: unsegmented mesenchyme Weak 7C Abnormally weak expression in presomitic mesoderm.
Specimen 7D: embryonic day 9.5 (more )
Note: Also stained for Uncx (assay MGI:6377213).
Structure Level Pattern Image Note
TS15: unsegmented mesenchyme Present 7D
Specimen 7E: embryonic day 9.5; Zic3Bn/Y (more )
Note: Also stained for Uncx (assay MGI:6377213).
Structure Level Pattern Image Note
TS15: unsegmented mesenchyme Present 7E
Specimen 7F: embryonic day 9.5; Zic2tm1Jaru/Zic2+, Zic3Bn/Y (more )
Note: Also stained for Uncx (assay MGI:6377213).
Structure Level Pattern Image Note
TS15: unsegmented mesenchyme Weak 7F Abnormally weak expression in presomitic mesoderm.
Specimen 7G: embryonic day 9.5; Zic2tm1Jaru/Zic2+, Zic3Bn/Y (more )
Note: Also stained for Uncx (assay MGI:6377213).
Structure Level Pattern Image Note
TS15: unsegmented mesenchyme Weak 7G Abnormally weak expression in presomitic mesoderm.
Specimen 9H wt: embryonic day 7.0 (more )
Structure Level Pattern Image Note
TS10: primitive streak Present 9H wt
Specimen 9H Bn/Y: embryonic day 7.0; Zic3Bn/Y (more )
Structure Level Pattern Image Note
TS10: primitive streak Present 9H Bn/Y
Specimen 9H kd/kd Bn/Y (left): embryonic day 7.0; Zic2tm1Jaru/Zic2tm1Jaru, Zic3Bn/Y (more )
Structure Level Pattern Image Note
TS10: primitive streak Weak Regionally restricted 9H kd/kd Bn/y (left) Authors report either a bent path or decreased intensity of expression.
Specimen 9H kd/kd Bn/Y (right): embryonic day 7.0; Zic2tm1Jaru/Zic2tm1Jaru, Zic3Bn/Y (more )
Structure Level Pattern Image Note
TS10: primitive streak Weak Regionally restricted 9H kd/kd Bn/y (right) Authors report either a bent path or decreased intensity of expression.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory