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Gene Expression Data
Assay Details
Assay
Reference: J:273053 Shih HP, et al., A Gene Regulatory Network Cooperatively Controlled by Pdx1 and Sox9 Governs Lineage Allocation of Foregut Progenitor Cells. Cell Rep. 2015 Oct 13;13(2):326-36
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6361337
Gene symbol: Sox9
Gene name: SRY (sex determining region Y)-box 9
Antibody: anti-Sox9
Detection system: Secondary antibody coupled to Alexa Fluor 488
Assay notes: Two antibodies were described, but the one used in this assay was not specified; either MGI:3056750 or MGI:5317435 could have been used.
Results
Specimen 3E': embryonic day 9.5; Sox9tm1Gsr/Sox9tm1Gsr (more )
Note: Double labeled: green - Sox9; red - Pdx1 (assay MGI:6361315).
Structure Level Pattern Image Note
TS15: pancreas primordium dorsal bud Present 3E'' , 3E'
Specimen 3F': embryonic day 9.5; Sox9tm1Gsr/Sox9tm1Gsr (more )
Note: Double labeled: green - Sox9; red - Pdx1 (assay MGI:6361315).
Structure Level Pattern Image Note
TS15: pancreas primordium ventral bud Present 3F' , 3F''
Specimen 3G': embryonic day 9.5; Sox9tm1Gsr/Sox9tm1Gsr, Tg(Foxa3-cre)1Khk/0 (more )
Note: Conditional mutant. Double labeled: green - Sox9; red - Pdx1 (assay MGI:6361315).
Structure Level Pattern Image Note
TS15: pancreas primordium dorsal bud Absent 3G' , 3G''
Specimen 3H': embryonic day 9.5; Sox9tm1Gsr/Sox9tm1Gsr, Tg(Foxa3-cre)1Khk/0 (more )
Note: Conditional mutant. Double labeled: green - Sox9; red - Pdx1 (assay MGI:6361315).
Structure Level Pattern Image Note
TS15: pancreas primordium ventral bud Absent 3H'' , 3H'
Specimen S1H: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: pancreas primordium Present S1H
Specimen S1I: embryonic day 10.5; Sox9tm1Gsr/Sox9+, Tg(Foxa3-cre)1Khk/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: pancreas primordium Present S1I
Specimen S1J: embryonic day 10.5; Pdx1tm2Cvw/Pdx1+ (more )
Structure Level Pattern Image Note
TS17: pancreas primordium Present S1J
Specimen S1K: embryonic day 10.5; Pdx1tm2Cvw/Pdx1+, Sox9tm1Gsr/Sox9+, Tg(Foxa3-cre)1Khk/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: pancreas primordium Present S1K
Specimen S1L: embryonic day 10.5; Sox9tm1Gsr/Sox9tm1Gsr, Tg(Foxa3-cre)1Khk/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: pancreas primordium Absent S1L
Specimen S1M: embryonic day 10.5; Pdx1tm2Cvw/Pdx1tm2Cvw (more )
Structure Level Pattern Image Note
TS17: pancreas primordium Present S1M
Specimen S1N: embryonic day 10.5; Pdx1tm2Cvw/Pdx1tm2Cvw, Sox9tm1Gsr/Sox9tm1Gsr, Tg(Foxa3-cre)1Khk/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: foregut Absent S1N
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory