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Gene Expression Data
Assay Details
Assay
Reference: J:104974 MacDonald JL, et al., Stage-specific induction of DNA methyltransferases in olfactory receptor neuron development. Dev Biol. 2005 Dec 15;288(2):461-73
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6360281
Gene symbol: Dnmt3b
Gene name: DNA methyltransferase 3B
Antibody: anti-Dnmt3b (IMG-184)
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen 3B: postnatal adult (more )
Note: Double labeled: red - Dnmt3b; green - Omp (assay MGI:6360278).
Structure Level Pattern Image Note
TS28: olfactory epithelium Present Regionally restricted 3B Expression in basally located cells. Not co-expressed with Omp.

Specimen 3C: postnatal adult (more )
Note: Double labeled: red - Dnmt3b; green - Ncam1 (assay MGI:6360282).
Structure Level Pattern Image Note
TS28: olfactory epithelium Present Regionally restricted 3C Expression in basally located cells. Not co-expressed with Ncam1.

Specimen 3D: postnatal adult (more )
Note: Double labeled: red - Dnmt3b; green - Krt5 (assay MGI:6360283).
Structure Level Pattern Image Note
TS28: olfactory epithelium Present Regionally restricted 3D Expression in basally located cells. Not co-expressed with cytokeratin 5/6

Specimen 3E: embryonic day 17.0 (more )
Note: Double labeled: red - Dnmt3b; green - Pcna (assay MGI:6360272).
Structure Level Pattern Image Note
TS25: olfactory epithelium Present Regionally restricted 3E Expression in some cells in middle layer of developing olfactory epithelium. Expression in basally located cells.

Specimen 3F: postnatal day 5 (more )
Note: Double labeled: red - Dnmt3b; green - Pcna (assay MGI:6360272).
Structure Level Pattern Image Note
TS28: olfactory epithelium Present Regionally restricted 3F Expression in some cells in middle layer of developing olfactory epithelium. Expression in basally located cells.

Specimen 3H: postnatal adult (more )
Note: Double labeled: red - Dnmt3b; green - Pcna (assay MGI:6360272).
Structure Level Pattern Image Note
TS28: olfactory epithelium Present Regionally restricted 3H Expression in majority of Pcna-expressing progenitors.

Specimen 3I: embryonic day 17.0 (more )
Note: Double labeled: red - Dnmt3b; green - Tubb3 (assay MGI:6360284).
Structure Level Pattern Image Note
TS25: olfactory epithelium Present Regionally restricted 3I Expression in some cells in middle layer of developing olfactory epithelium. Expression in basally located cells.

Specimen 3J: postnatal day 5 (more )
Note: Double labeled: red - Dnmt3b; green - Tubb3 (assay MGI:6360284).
Structure Level Pattern Image Note
TS28: olfactory epithelium Present Regionally restricted 3J Expression in some cells in middle layer of developing olfactory epithelium. Expression in basally located cells.

Specimen 3L: postnatal adult (more )
Note: Double labeled: red - Dnmt3b; green - Tubb3 (assay MGI:6360284).
Structure Level Pattern Image Note
TS28: olfactory epithelium Present Regionally restricted 3L Co-expression with Tubb3 rarely observed.

Specimen 6D: embryonic day 17.0 (more )
Note: Double labeled: red - Dnmt3b: green - Hdac2 (assay MGI:6360288).
Structure Level Pattern Image Note
TS25: olfactory epithelium Present Regionally restricted 6D Expression in basally-situated cells.

Specimen 6E: postnatal day 5 (more )
Note: Double labeled: red - Dnmt3b: green - Hdac2 (assay MGI:6360288).
Structure Level Pattern Image Note
TS28: olfactory epithelium Present Regionally restricted 6E Expression in basally-situated cells.

Specimen 6F: postnatal adult (more )
Note: Double labeled: red - Dnmt3b: green - Hdac2 (assay MGI:6360288).
Structure Level Pattern Image Note
TS28: olfactory epithelium Present Regionally restricted 6F Expression in basally-situated cells.

Specimen 7D: postnatal adult (more )
Note: Double labeled: red - Dnmt3b: green - Hdac1 (assay MGI:6360289)
Structure Level Pattern Image Note
TS28: olfactory epithelium Present Regionally restricted 7D Expression in apical and basal cell layers.

Specimen 7H: postnatal adult (more )
Note: Double labeled: red - Dnmt3b: green - Hdac2 (assay MGI:6360288).
Structure Level Pattern Image Note
TS28: olfactory epithelium Present 7H

Specimen 8A: postnatal day 5 (more )
Note: Double labeled: red - Dnmt3b; green - Pcna (assay MGI:6360272).
Structure Level Pattern Image Note
TS28: vomeronasal organ epithelium Present Regionally restricted 8A Expression in nuclei of vomeronasal organ, co-expressed with Pcna in vomeronasal epithelium, but not in respiratory epithelium.

Specimen 8C: embryonic day 17.0 (more )
Note: Double labeled: red - Dnmt3b; green - Tubb3 (assay MGI:6360284).
Structure Level Pattern Image Note
TS25: retina outer nuclear layer Present Regionally restricted 8C Expression in subpopulation of cells in outer nerve layer. Not expressed in nuclei of Tubb3-expressing neurons

Specimen 8E: embryonic day 17.0 (more )
Note: Double labeled: red - Dnmt3b; green - Pcna (assay MGI:6360272).
Structure Level Pattern Image Note
TS25: tongue papillae Present Regionally restricted 8E Expression in developing taste buds, co-expressed with Pcna.

Specimen 8F: embryonic day 17.0 (more )
Note: Double labeled: red - Dnmt3b; green - Tubb3 (assay MGI:6360284).
Structure Level Pattern Image Note
TS25: cerebral cortex Present Regionally restricted 8F Expression in subset of cells throughout brain cortex and rostral migratory stream.
TS25: rostral migratory stream Present Regionally restricted 8F Expression in subset of cells throughout brain cortex and rostral migratory stream.


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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory