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Gene Expression Data
Assay Details
Assay
Reference: J:181271 Westmoreland JJ, et al., Dynamic distribution of claudin proteins in pancreatic epithelia undergoing morphogenesis or neoplastic transformation. Dev Dyn. 2012 Mar;241(3):583-94
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6343213
Gene symbol: Cldn7
Gene name: claudin 7
Antibody: anti-Claudin-7 (E10594)
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 6A: embryonic day 10.5 (more )
Note: Double labeled: red - Cldn7; green - Tjp1 (assay MGI:6343238).
Structure Level Pattern Image Note
TS17: pancreas primordium Present Regionally restricted 6A Expression was detected throughout the membrane of pancreatic epithelium.

Specimen 6B: embryonic day 12.5 (more )
Note: Double labeled: red - Cldn7; green - Tjp1 (assay MGI:6343238).
Structure Level Pattern Image Note
TS20: pancreas Present Regionally restricted 6B Expression was detected in the lateral membranes and the Tjp1-positive tight junctions.

Specimen 6C: embryonic day 15.5 (more )
Note: Double labeled: red - Cldn7; green - Tjp1 (assay MGI:6343238).
Structure Level Pattern Image Note
TS23: pancreas Present Regionally restricted 6C Expression was detected in the lateral membranes and the Tjp1-positive tight junctions.

Specimen not shown: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: islets of Langerhans Present Regionally restricted Expression was detected in the lateral membranes and the Tjp1-positive tight junctions.
TS26: pancreatic acinus Present Regionally restricted Expression was detected in the lateral membranes and the Tjp1-positive tight junctions.
TS26: pancreatic duct Present Regionally restricted Expression was detected in the lateral membranes and the Tjp1-positive tight junctions.

Specimen 6D: postnatal day 5 (more )
Note: Double labeled: red - Cldn7; green - Tjp1 (assay MGI:6343238).
Structure Level Pattern Image Note
TS28: pancreatic duct Present Regionally restricted 6D Expression was detected in the lateral membrane of ductal cells and colocalized with Tjp1 in tight junctions of duct epithelial cells.

Specimen 6E: postnatal day 5 (more )
Note: Double labeled: red - Cldn7; green - Tjp1 (assay MGI:6343238).
Structure Level Pattern Image Note
TS28: pancreatic acinus Present Regionally restricted 6E Expression was detected in the lateral membrane of acinar cells. There was limited association with Tjp1 in acinar tight junctions.

Specimen 6F: postnatal day 5 (more )
Note: Double labeled: red - Cldn7; green - Tjp1 (assay MGI:6343238).
Structure Level Pattern Image Note
TS28: islets of Langerhans Weak Regionally restricted 6F Low, but detectable expression was detected in the lateral membrane and possible tight junctions of islet cells.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory