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Gene Expression Data
Assay Details
Assay
Reference: J:268084 Saha A, et al., Class I histone deacetylases in retinal progenitors and differentiating ganglion cells. Gene Expr Patterns. 2018 Dec;30:37-48
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6342233
Gene symbol: Hdac3
Gene name: histone deacetylase 3
Antibody: anti-HDAC3 (3949)
Detection system: Secondary antibody
Results
Specimen 5A: embryonic day 16.5 (more )
Note: Double labeled: red - Hdac3 ; green - Sox2 (assay MGI:6342226).
Structure Level Pattern Image Note
TS24: retina Present 5A
TS24: retina layer Weak Regionally restricted 5A Expression is in progenitor nuclei primarily at the scleral edge.
Specimen 5B: embryonic day 16.5 (more )
Note: Double labeled: red - Hdac3 ; green - Pou4f3 (assay MGI:6342227).
Structure Level Pattern Image Note
TS24: retina Present 5B
TS24: retina layer Weak Regionally restricted 5B Expression is in a subpopulation of retinal ganglion cell nuclei close to the vitreous and is absent in migrating retinal ganglion cells.
Specimen 5C: postnatal day 5 (more )
Note: Double labeled: red - Hdac3 ; green - Sox2 (assay MGI:6342226).
Structure Level Pattern Image Note
TS28: retina inner nuclear layer Present Regionally restricted 5C Expression is in cholinergic amacrine cells and retinal astrocytes.
TS28: retina outer nuclear layer Present Regionally restricted 5C Expression is in cholinergic amacrine cells and retinal astrocytes.
Specimen 5D: postnatal day 5 (more )
Note: Double labeled: red - Hdac3 ; green - Pou4f3 (assay MGI:6342227).
Structure Level Pattern Image Note
TS28: retina inner nuclear layer Present Regionally restricted 5D Expression is in cholinergic amacrine cells and retinal astrocytes.
TS28: retina outer nuclear layer Present Regionally restricted 5D Expression is in cholinergic amacrine cells and retinal astrocytes.
Specimen 5E: postnatal day 30 (more )
Note: Double labeled: red - Hdac3 ; green - Sox2 (assay MGI:6342226).
Structure Level Pattern Image Note
TS28: retina inner nuclear layer Strong Regionally restricted 5E Expression is in cholinergic amacrine cells and retinal astrocytes and is absent in Mller glial cells.
TS28: retina outer nuclear layer Strong Regionally restricted 5E Expression is in cholinergic amacrine cells and retinal astrocytes and is absent in Mller glial cells.
Specimen 5F: postnatal day 30 (more )
Note: Double labeled: red - Hdac3 ; green - Pou4f1 (assay MGI:6342228).
Structure Level Pattern Image Note
TS28: retina inner nuclear layer Present 5F
TS28: retina outer nuclear layer Present 5F
Specimen S2A: embryonic day 16.5 (more )
Note: Double labeled: red - Hdac3 ; green - Pou4f3 (assay MGI:6342227).
Structure Level Pattern Image Note
TS24: retina Present S2A
Specimen S2C: postnatal day 30 (more )
Note: Double labeled: red - Hdac3 ; green - Sox2 (assay MGI:6342226).
Structure Level Pattern Image Note
TS28: retina inner nuclear layer Present S2C
TS28: retina outer nuclear layer Present S2C
Specimen S3A: embryonic day 16.5 (more )
Note: Double labeled: red - Hdac3 ; green - Pou4f3 (assay MGI:6342227).
Structure Level Pattern Image Note
TS24: retina Present S3A
TS24: retina layer Weak Regionally restricted S3A Expression is in progenitor nuclei primarily at the scleral edge and in a subpopulation of retinal ganglion cell nuclei close to the vitreous and is absent in migrating retinal ganglion cells.
Specimen S3C: postnatal day 30 (more )
Note: Double labeled: red - Hdac3 ; green - Sox2 (assay MGI:6342226).
Structure Level Pattern Image Note
TS28: retina inner nuclear layer Present S3C
TS28: retina outer nuclear layer Present S3C
TS28: retina ganglion cell layer Strong Regionally restricted S3C Expression is in cholinergic amacrine cells and retinal astrocytes and is absent in Mller glial cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory