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Gene Expression Data
Assay Details
Assay
Reference: J:241573 Pui HP, et al., Gonocytes-to-spermatogonia transition initiates prior to birth in murine testes and it requires FGF signaling. Mech Dev. 2017 Apr;144(Pt B):125-139
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6305361
Gene symbol: Gfra1
Gene name: glial cell line derived neurotrophic factor family receptor alpha 1
Results
Specimen 1B E17.5: embryonic day 17.5 (more )
Note: Double labeled: red - Gfra1; green - Gcna (assay MGI:6305358).
Structure Level Pattern Image Note
TS25: germ cell of testis Absent 1B E17.5 GFRAI+TRA98
Specimen 1B E18.5: embryonic day 18.5 (more )
Note: Double labeled: red - Gfra1; green - Gcna (assay MGI:6305358).
Structure Level Pattern Image Note
TS26: seminiferous cord Present 1B E18.5 GFRAI+TRA98 Expression was detected in nascent spermatogonia.
Specimen 1B P0.5: postnatal day 0.5 (more )
Note: Double labeled: red - Gfra1; green - Gcna (assay MGI:6305358).
Structure Level Pattern Image Note
TS27: spermatogonium Present 1B P0.5 GFRAI+TRA98
Specimen 1B P1.5: postnatal day 1.5 (more )
Note: Double labeled: red - Gfra1; green - Gcna (assay MGI:6305358).
Structure Level Pattern Image Note
TS27: spermatogonium Present 1B P1.5 GFRAI+TRA98
Specimen 2A: embryonic day 18.5 (more )
Note: Double labeled: red - Gfra1; green - Zbtb16 (assay MGI:6305364).
Structure Level Pattern Image Note
TS26: germ cell of testis Present Regionally restricted 2A GFRAI , 2A GFRAI+PLZF Expression was detected in nascent spermatogonia, which co-expressed Zbtb16.
Specimen 3C E17.5: embryonic day 17.5 (more )
Note: Double labeled: red - Gfra1; green - Foxo1 (assay MGI:6306311).
Structure Level Pattern Image Note
TS25: germ cell of testis Absent 3C E17.5 GFRAI , 3C E17.5 GFRAI+FOXO1+DAPI
Specimen 3C E18.5: embryonic day 18.5 (more )
Note: Double labeled: red - Gfra1; green - Foxo1 (assay MGI:6306311).
Structure Level Pattern Image Note
TS26: germ cell of testis Present 3C E18.5 GFRAI+FOXO1+DAPI , 3C E18.5 GFRAI Expression correlated with the Foxo1 nuclear to cytoplasmic translocation expression. The majority of gonocytes with cytoplasmic Foxo1 expression showed Gfra1 expression.
Specimen 3C P0.5: postnatal day 0.5 (more )
Note: Double labeled: red - Gfra1; green - Foxo1 (assay MGI:6306311).
Structure Level Pattern Image Note
TS27: germ cell of testis Present 3C P0.5 GFRAI+FOXO1+DAPI , 3C P0.5 GFRAI
Specimen 3C P1.5: postnatal day 1.5 (more )
Note: Double labeled: red - Gfra1; green - Foxo1 (assay MGI:6306311).
Structure Level Pattern Image Note
TS27: germ cell of testis Present 3C P1.5 GFRAI , 3C P1.5 GFRAI+FOXO1+DAPI
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory