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Gene Expression Data
Assay Details
Assay
Reference: J:187541 Schievenbusch S, et al., Neighbor of punc e 11: expression pattern of the new hepatic stem/progenitor cell marker during murine liver development. Stem Cells Dev. 2012 Sep 20;21(14):2656-66
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6278256
Gene symbol: Afp
Gene name: alpha fetoprotein
Antibody: AFP antibody
Assay notes: Tissue sections were fixed in ice-cold acetone.
Results
Specimen 3C/D: embryonic day 14.5 (more )
Note: Triple labeled: green - Afp; yellow - Nope (Igdcc4; assay MGI:6278253); red - E-Cadherin (Cdh1; assay MGI:6278255).
Structure Level Pattern Image Note
TS22: liver Present Regionally restricted 3D , 3C Expression restricted to bipotential hepatoblasts.

Specimen 3G/H: embryonic day 17.5 (more )
Note: Triple labeled: green - Afp; yellow - Nope (Igdcc4; assay MGI:6278253); red - E-Cadherin (Cdh1; assay MGI:6278255).
Structure Level Pattern Image Note
TS25: liver Present Regionally restricted 3H , 3G Expression in differentiated committed progenitor cells.

Specimen 3K/L: postnatal week 1 (more )
Note: Triple labeled: green - Afp; yellow - Nope (Igdcc4; assay MGI:6278253); red - E-Cadherin (Cdh1; assay MGI:6278255).
Structure Level Pattern Image Note
TS28: liver Absent 3K , 3L Expression no longer traceable at 1 wpn.

Specimen 3O/P: postnatal adult (more )
Note: Triple labeled: green - Afp; yellow - Nope (Igdcc4; assay MGI:6278253); red - E-Cadherin (Cdh1; assay MGI:6278255).
Structure Level Pattern Image Note
TS28: liver Absent 3O , 3P No expression in differentiated hepatocytes.

Specimen 4C/D: embryonic day 14.5 (more )
Note: Triple labeled: green - Afp; yellow - Nope (Igdcc4; assay MGI:6278253); red - CK19 (Krt19; assay MGI:6278257).
Structure Level Pattern Image Note
TS22: liver Present Regionally restricted 4D , 4C Expression in bipotential hepatoblasts.

Specimen 4G/H: embryonic day 17.5 (more )
Note: Triple labeled: green - Afp; yellow - Nope (Igdcc4; assay MGI:6278253); red - CK19 (Krt19; assay MGI:6278257).
Structure Level Pattern Image Note
TS25: bile duct Absent 4G , 4H

Specimen 4K/L: postnatal week 1 (more )
Note: Triple labeled: green - Afp; yellow - Nope (Igdcc4; assay MGI:6278253); red - CK19 (Krt19; assay MGI:6278257).
Structure Level Pattern Image Note
TS28: bile duct Absent 4L , 4K No expression in early cholangiocytes.

Specimen 4O/P: postnatal adult (more )
Note: Triple labeled: green - Afp; yellow - Nope (Igdcc4; assay MGI:6278253); red - CK19 (Krt19; assay MGI:6278257).
Structure Level Pattern Image Note
TS28: bile duct Absent 4P , 4O No expression in differentiated cholangiocytes.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/28/2024
MGI 6.13
The Jackson Laboratory