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Gene Expression Data
Assay Details
Assay
Reference: J:187541 Schievenbusch S, et al., Neighbor of punc e 11: expression pattern of the new hepatic stem/progenitor cell marker during murine liver development. Stem Cells Dev. 2012 Sep 20;21(14):2656-66
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6278253
Gene symbol: Igdcc4
Gene name: immunoglobulin superfamily, DCC subclass, member 4
Antibody: Nope antibody
Detection system: Cy3
Assay notes: Tissue sections were fixed in ice-cold acetone.
Results
Specimen 3A/D: embryonic day 14.5 (more )
Note: Triple labeled: yellow - Nope (Igdcc4); red - E-Cadherin (Cdh1; assay MGI:6278255); green - Afp (assay MGI:6278256).
Structure Level Pattern Image Note
TS22: liver Present Regionally restricted 3A , 3D Expression restricted to bipotential hepatoblasts.

Specimen 3E/H: embryonic day 17.5 (more )
Note: Triple labeled: yellow - Nope (Igdcc4); red - E-Cadherin (Cdh1; assay MGI:6278255); green - Afp (assay MGI:6278256).
Structure Level Pattern Image Note
TS25: liver Present Regionally restricted 3H , 3E Expression in differentiated committed progenitor cells.

Specimen 3I/L: postnatal week 1 (more )
Note: Triple labeled: yellow - Nope (Igdcc4); red - E-Cadherin (Cdh1; assay MGI:6278255); green - Afp (assay MGI:6278256).
Structure Level Pattern Image Note
TS28: liver Present Regionally restricted 3I , 3L Expression in early Cdh1-positive hepatocytes.

Specimen 3M/P: postnatal adult (more )
Note: Triple labeled: yellow - Nope (Igdcc4); red - E-Cadherin (Cdh1; assay MGI:6278255); green - Afp (assay MGI:6278256).
Structure Level Pattern Image Note
TS28: liver Present Regionally restricted 3P , 3M No expression in differentiated hepatocytes.

Specimen 4A/D: embryonic day 14.5 (more )
Note: Triple labeled: yellow - Nope (Igdcc4); red - CK19 (Krt19; assay MGI:6278257); green - Afp (assay MGI:6278256).
Structure Level Pattern Image Note
TS22: liver Present Regionally restricted 4D , 4A Expression restricted to bipotential hepatoblasts.

Specimen 4E/H: embryonic day 17.5 (more )
Note: Triple labeled: yellow - Nope (Igdcc4); red - CK19 (Krt19; assay MGI:6278257); green - Afp (assay MGI:6278256).
Structure Level Pattern Image Note
TS25: liver Present Regionally restricted 4H , 4E Expression not restricted to hepatocyte progenitor cells.
TS25: bile duct Present Regionally restricted 4E , 4H Expression clearly detectable in early bile ducts (committed cholangiocytic progenitor cells).

Specimen 4I/L: postnatal week 1 (more )
Note: Triple labeled: yellow - Nope (Igdcc4); red - CK19 (Krt19; assay MGI:6278257); green - Afp (assay MGI:6278256).
Structure Level Pattern Image Note
TS28: bile duct Present Regionally restricted 4L , 4I Expression in early cholangiocytes.

Specimen 4M/P: postnatal adult (more )
Note: Triple labeled: yellow - Nope (Igdcc4); red - CK19 (Krt19; assay MGI:6278257); green - Afp (assay MGI:6278256).
Structure Level Pattern Image Note
TS28: bile duct Present Regionally restricted 4M , 4P Expression in differentiated cholangiocytes.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory