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Gene Expression Data
Assay Details
Assay
Reference: J:264159 Zurner M, et al., Analyses of the spatiotemporal expression and subcellular localization of liprin-alpha proteins. J Comp Neurol. 2011 Oct 15;519(15):3019-39
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6256577
Gene symbol: Ppfia2
Gene name: protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
Antibody: Liprin-alpha2 antibody
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 5B: postnatal week 7-10 (more )
Structure Level Pattern Image Note
TS28: cerebellum granule cell layer Present Punctate 5B
TS28: cerebellum molecular layer Present 5B
TS28: cerebellum Purkinje cell layer Present 5B Expression is in Purkinje cell bodies.
Specimen 6D: postnatal week 7-10 (more )
Note: Double labeled: green - Ppfia2; purple - Syn1 (assay MGI:6256575).
Structure Level Pattern Image Note
TS28: cerebellum granule cell layer Present Punctate 6F , 6D
TS28: cerebellum molecular layer Strong 6D , 6F
TS28: cerebellum Purkinje cell layer Present 6F , 6D Expression is in Purkinje cell bodies.
Specimen 7B: postnatal week 7-10 (more )
Structure Level Pattern Image Note
TS28: hippocampus Present 7B Expression is strongest along the mossy fibers.
TS28: hippocampus CA3 Strong Regionally restricted 7B Expression is at the mossy fiber synapses.
Specimen 8B: postnatal week 7-10 (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb external plexiform layer Present 8B
TS28: main olfactory bulb glomerular layer Present 8B
Specimen 9A: postnatal week 7-10 (more )
Structure Level Pattern Image Note
TS28: corpus striatum Present Widespread 9A
Specimen 9D: postnatal week 7-10 (more )
Structure Level Pattern Image Note
TS28: thalamus Weak 9D
Specimen 10D: postnatal week 10 (more )
Note: Double labeled: green - Ppfia2; purple - Ctbp2 (assay MGI:6256576).
Structure Level Pattern Image Note
TS28: photoreceptor layer inner segment Present 10F , 10D
TS28: photoreceptor layer outer segment Present 10F , 10D
TS28: retina inner plexiform layer Present 10F , 10D
TS28: retina inner nuclear layer Present Regionally restricted 10D , 10F Expression is in somata.
Specimen not shown: postnatal week 7-10 (more )
Structure Level Pattern Image Note
TS28: brainstem Present Uniform
TS28: cerebral cortex Present Uniform
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory