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Gene Expression Data
Assay Details
Assay
Reference: J:262410 Tanabe S, et al., B-1a lymphocytes promote oligodendrogenesis during brain development. Nat Neurosci. 2018 Apr;21(4):506-516
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6196534
Gene symbol: Ptprc
Gene name: protein tyrosine phosphatase receptor type C
Antibody: anti-CD45R clone RA3-6B2
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 1c: postnatal day 1; Cd19tm1(cre)Cgn/Cd19+, Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Double labeled: green - Ptprc; red - Cre reporter.
Structure Level Pattern Image Note
TS27: choroid plexus Present 1c right , 1c left Double-positive (tdTomato+,Ptprc+) B-cells were localized in the choroid plexus.
Specimen 1d: postnatal day 1; Cd19tm1(cre)Cgn/Cd19+, Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Double labeled: green - Ptprc; red - Cre reporter.
Structure Level Pattern Image Note
TS27: meninges Present 1d left , 1d right Double-positive (tdTomato+,Ptprc+) B-cells were localized in the meningeal space.
Specimen 1e: postnatal day 1; Cd19tm1(cre)Cgn/Cd19+, Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Double labeled: green - Ptprc; red - Cre reporter.
Structure Level Pattern Image Note
TS27: lateral ventricle ependyma Present Regionally restricted 1e left , 1e right Double-positive (tdTomato+,Ptprc+) B-cells were localized in the wall of the lateral ventricle.
Specimen 1f: postnatal day 1; Cd19tm1(cre)Cgn/Cd19+, Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Double labeled: green - Ptprc; red - Cre reporter.
Structure Level Pattern Image Note
TS27: cerebral cortex Present Single cells 1f right , 1f left Double-positive (tdTomato+,Ptprc+) B-cells were rarely detected in the brain parenchyma, including the cerebral cortex.
Specimen 1g: postnatal day 1; Cd19tm1(cre)Cgn/Cd19+, Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Double labeled: green - Ptprc; red - Cre reporter.
Structure Level Pattern Image Note
TS27: hindbrain meninges Present Regionally restricted 1g left , 1g right , 1g' left , 1g' right Double-positive (tdTomato+,Ptprc+) B-cells were localized in the meningeal space of the cerebellum.
TS27: cerebellum Absent 1g' left , 1g left B-cells were not localized in the parenchyma of the cerebellum.
Specimen 1h: postnatal day 1; Cd19tm1(cre)Cgn/Cd19+, Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Double labeled: green - Ptprc; red - Cre reporter.
Structure Level Pattern Image Note
TS27: spinal cord meninges Present 1h' right , 1h right , 1h left , 1h' left Double-positive (tdTomato+,Ptprc+) B-cells were localized in the meningeal space of the spinal cord.
TS27: spinal cord Absent 1h left , 1h' left B-cells were not localized in the parenchyma of the spinal cord.
Specimen 1r: postnatal day 5 (more )
Note: Double labeled: green - Ptprc; red - Ighm (assay MGI:6196546).
Structure Level Pattern Image Note
TS28: brain Present 1r left , 1r right Expression was detected in B-cells.
Specimen 1s: postnatal adult (more )
Note: Double labeled: green - Ptprc; red - Ighm (assay MGI:6196546).
Structure Level Pattern Image Note
TS28: spleen Present 1s left , 1s right Expression was detected in B-cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory