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Gene Expression Data
Assay Details
Assay
Reference: J:130203 Ijpenberg A, et al., Wt1 and retinoic acid signaling are essential for stellate cell development and liver morphogenesis. Dev Biol. 2007 Dec 1;312(1):157-70
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6188102
Gene symbol: Rxra
Gene name: retinoid X receptor alpha
Results
Specimen 4E: embryonic day 12.5 (more )
Note: Double labeled: red - Rxra; green - Pcna (assay MGI:6188101).
Structure Level Pattern Image Note
TS20: liver Present Regionally restricted 4E Authors report co-localization of expression with Pcna.
Specimen 4F: embryonic day 12.5; Wt1tm1Jae/Wt1tm1Jae (more )
Note: Double labeled: red - Rxra; green - Pcna (assay MGI:6188101).
Structure Level Pattern Image Note
TS20: liver Present Regionally restricted 4F Authors report co-localization of expression with Pcna.
Specimen 5E: embryonic day 12.5 (more )
Note: Double labeled: red - Rxra; green - Acta2 (assay MGI:6188090).
Structure Level Pattern Image Note
TS20: liver vascular element Present Regionally restricted 5E Co-localization of expression with smooth muscle cell alpha-actin in walls of large vessels.
TS20: liver parenchyma Strong Regionally restricted 5E Authors report more intense expression in cells not associated with sinusoids.
Specimen 5F: embryonic day 12.5 (more )
Note: Double labeled: red - Rxra; green - Acta2 (assay MGI:6188090).
Structure Level Pattern Image Note
TS20: liver vascular element Present Regionally restricted 5F Co-localization of expression with smooth muscle cell alpha-actin in walls of large vessels.
TS20: liver parenchyma Strong Regionally restricted 5F Authors report more intense expression in cells not associated with sinusoids.
Specimen 5G: embryonic day 12.5; Wt1tm1Jae/Wt1tm1Jae (more )
Note: Double labeled: red - Rxra; green - Acta2 (assay MGI:6188090).
Structure Level Pattern Image Note
TS20: liver vascular element Present Regionally restricted 5G Co-localization of expression with smooth muscle cell alpha-actin.
TS20: liver sinusoid Weak 5G Less intense expression in cells usually located in the sinusoids.
Specimen 5H: embryonic day 12.5; Wt1tm1Jae/Wt1tm1Jae (more )
Note: Double labeled: red - Rxra; green - Acta2 (assay MGI:6188090).
Structure Level Pattern Image Note
TS20: liver vascular element Present Regionally restricted 5H Co-localization of expression with smooth muscle cell alpha-actin.
TS20: liver sinusoid Weak Regionally restricted 5H Less intense expression in cells usually located in the sinusoids.
TS20: intestine Present Regionally restricted 5H Expression in intestinal musculature.
Specimen 5I: embryonic day 13.5 (more )
Note: Double labeled: red - Rxra; green - Acta2 (assay MGI:6188090).
Structure Level Pattern Image Note
TS21: liver vascular element Present Regionally restricted 5I Co-localization of expression with smooth muscle cell alpha-actin in walls of large vessels.
TS21: liver parenchyma Strong Regionally restricted 5I Authors report more intense expression in cells not associated with sinusoids.
Specimen 5J: embryonic day 13.5; Wt1tm1Jae/Wt1tm1Jae (more )
Note: Double labeled: red - Rxra; green - Acta2 (assay MGI:6188090).
Structure Level Pattern Image Note
TS21: liver vascular element Present Regionally restricted 5J Co-localization of expression with smooth muscle cell alpha-actin.
TS21: liver parenchyma Weak 5J Less intense expression in cells usually located in the sinusoids.
Specimen 5K: embryonic day 13.5 (more )
Note: Double labeled: red - Rxra; green - Acta2 (assay MGI:6188090).
Structure Level Pattern Image Note
TS21: dorsal aorta Present Regionally restricted 5K
Specimen 5L: embryonic day 13.5 (more )
Note: Double labeled: red - Rxra; green - Ter119 (Ly76 assay MGI:6188095).
Structure Level Pattern Image Note
TS21: liver Present Regionally restricted 5L Authors report no co-localization of expression with erythroblast marker Terr119 (Ly76).
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/28/2024
MGI 6.13 		The Jackson Laboratory