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Gene Expression Data
Assay Details
Assay
Reference: J:236149 Edwards W, et al., Identification of a novel progenitor cell marker, grainyhead-like 2 in the developing pituitary. Dev Dyn. 2016 Nov;245(11):1097-1106
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6156393
Gene symbol: Cdh1
Gene name: cadherin 1
Antibody: anti-E-Cadherin
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to Cy2
Assay notes: A Zinc fixative was used.
Results
Specimen 6A: postnatal day 1 (more )
Note: Double labeled: green - Cdh1; red - Grhl2 (assay MGI:6155596).
Structure Level Pattern Image Note
TS27: adenohypophysis Strong Regionally restricted 6B , 6A Expression is throughout the anterior pituitary and is concentrated in the cleft cells.
TS27: adenohypophysis pars intermedia Strong Regionally restricted 6B , 6A Expression is throughout the anterior pituitary and is concentrated in the cleft cells.

Specimen 6C: postnatal day 1 (more )
Note: Double labeled: green - Cdh1; red - Grhl2 (assay MGI:6155596).
Structure Level Pattern Image Note
TS27: adenohypophysis pars intermedia Strong Regionally restricted 6C , 6D Expression is throughout and is concentrated in the cleft cells.

Specimen 6E: postnatal day 1 (more )
Note: Double labeled: green - Cdh1; red - Grhl2 (assay MGI:6155596).
Structure Level Pattern Image Note
TS27: adenohypophysis Strong Regionally restricted 6E , 6F Expression is is throughout and is concentrated in the cleft cells.

Specimen 6G: postnatal day 1; Foxg1tm1(cre)Skm/Foxg1+, Notch2tm3Grid/Notch2tm3Grid (more )
Note: Conditional mutant. Double labeled: green - Cdh1; red - Grhl2 (assay MGI:6155596).
Structure Level Pattern Image Note
TS27: adenohypophysis Present Regionally restricted 6H , 6G Expression is the same as in wild-type.
TS27: adenohypophysis pars intermedia Weak Single cells 6G , 6H

Specimen 6I: postnatal day 1; Foxg1tm1(cre)Skm/Foxg1+, Notch2tm3Grid/Notch2tm3Grid (more )
Note: Conditional mutant. Double labeled: green - Cdh1; red - Grhl2 (assay MGI:6155596).
Structure Level Pattern Image Note
TS27: adenohypophysis pars intermedia Weak Single cells 6J , 6I

Specimen 6K: postnatal day 1; Foxg1tm1(cre)Skm/Foxg1+, Notch2tm3Grid/Notch2tm3Grid (more )
Note: Conditional mutant. Double labeled: green - Cdh1; red - Grhl2 (assay MGI:6155596).
Structure Level Pattern Image Note
TS27: adenohypophysis Present Regionally restricted 6L , 6K Expression is the same as in wild-type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory