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Gene Expression Data
Assay Details
Assay
Reference: J:239876 Xu Q, et al., Maternal BCAS2 protects genomic integrity in mouse early embryonic development. Development. 2015 Nov 15;142(22):3943-53
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5910434
Gene symbol: Bcas2
Gene name: BCAS2 pre-mRNA processing factor
Antibody: anti-BCAS2 (10414)
Detection system: Secondary antibody
Results
Specimen 1C GV: postnatal adult (more )
Note: Germinal vesicle oocytes.
Structure Level Pattern Image Note
TS28: primary oocyte Present 1C GV Expression is nuclear.
Specimen 1C MII: postnatal adult (more )
Note: Metaphase II oocytes.
Structure Level Pattern Image Note
TS28: secondary oocyte Present 1C MII Expression is cytoplasmic.
Specimen 1C 1C: embryonic day 0.5 (more )
Note: 1-cell zygote.
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Present 1C 1C Expression is nuclear.
Specimen 1C 2C: embryonic day 1.0 (more )
Note: 2-cell embryo.
Structure Level Pattern Image Note
TS2: 2-cell stage embryo Present 1C 2C Expression is nuclear.
Specimen 1C 4C: embryonic day 1.0 (more )
Note: 4-cell embryo.
Structure Level Pattern Image Note
TS3: 4-cell stage embryo Present 1C 4C Expression is nuclear.
Specimen 1C MO: embryonic day 3.0 (more )
Note: Morula stage embryo.
Structure Level Pattern Image Note
TS4: compacted morula Present 1C MO Expression is nuclear.
Specimen 1C BL: embryonic day 3.5 (more )
Note: Blastocyst stage embryo.
Structure Level Pattern Image Note
TS4: inner cell mass Present 1C BL Expression is nuclear.
Specimen 2A PN2: embryonic day 0.5 (more )
Note: 1-cell zygote 23 h post-hCG. Pronuclear stage 2. Double labeled: green - Bcas2; red - H2ax (assay MGI:5910436).
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Present 2A PN2 Merge , 2A PN2 BCAS2
Specimen 2A Mid PN3: embryonic day 0.5 (more )
Note: 1-cell zygote 25 h post-hCG. Pronuclear stage mid 3. Double labeled: green - Bcas2; red - H2ax (assay MGI:5910436).
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Present 2A Mid PN3 BCAS2 , 2A Mid PN3 Merge Expression is stronger in paternal pronuclei than in maternal pronuclei.
Specimen 2A PN4: embryonic day 0.5 (more )
Note: 1-cell zygote 28 h post-hCG. Pronuclear stage 4. Double labeled: green - Bcas2; red - H2ax (assay MGI:5910436).
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Present 2A PN4 BCAS2 , 2A PN4 Merge Expression is stronger in paternal pronuclei than in maternal pronuclei.
Specimen 2A late PN5: embryonic day 0.5 (more )
Note: 1-cell zygote 30 h post-hCG. Pronuclear stage late 5. Double labeled: green - Bcas2; red - H2ax (assay MGI:5910436).
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Present 2A Late PN5 BCAS2 , 2A Late PN5 Merge Expression is stronger in paternal pronuclei than in maternal pronuclei.
Specimen 2B PN2: embryonic day 0.5 (more )
Note: 1-cell zygote 23 h post-hCG. Pronuclear stage 2. Double labeled: green - Bcas2; red - H2ax (assay MGI:5910436). Specimens were treated with Triton for 1 minute prior to fixation.
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Present 2B PN2 BCAS2 , 2B PN2 Merge
Specimen 2B Late PN3: embryonic day 0.5 (more )
Note: 1-cell zygote 25 h post-hCG. Pronuclear stage late 3. Double labeled: green - Bcas2; red - H2ax (assay MGI:5910436). Specimens were treated with Triton for 1 minute prior to fixation.
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Present 2B Late PN3 BCAS2 , 2B Late PN3 Merge
Specimen 2B PN4: embryonic day 0.5 (more )
Note: 1-cell zygote 28 h post-hCG. Pronuclear stage 4. Double labeled: green - Bcas2; red - H2ax (assay MGI:5910436). Specimens were treated with Triton for 1 minute prior to fixation.
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Present 2B PN4 BCAS2 , 2B PN4 Merge
Specimen 2B Early PN5: embryonic day 0.5 (more )
Note: 1-cell zygote 30 h post-hCG. Pronuclear stage early 5. Double labeled: green - Bcas2; red - H2ax (assay MGI:5910436). Specimens were treated with Triton for 1 minute prior to fixation.
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Present 2B Early PN5 BCAS2 , 2B Early PN5 Merge
Specimen 2B Late PN5: embryonic day 0.5 (more )
Note: 1-cell zygote 30 h post-hCG. Pronuclear stage late 5. Double labeled: green - Bcas2; red - H2ax (assay MGI:5910436). Specimens were treated with Triton for 1 minute prior to fixation.
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Present 2B Late PN5 BCAS2 , 2B Late PN5 Merge
Specimen 3D Control: postnatal adult; Bcas2tm1.1Lil/Bcas2+, Tg(Zp3-cre)3Mrt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: germ cell of ovary Present 3D Control
Specimen 3D BcAs2mNull: postnatal adult; Bcas2tm1.1Lil/Bcas2tm1.1Lil, Tg(Zp3-cre)3Mrt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: germ cell of ovary Trace 3D Bcas2mNull
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory