About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:239876 Xu Q, et al., Maternal BCAS2 protects genomic integrity in mouse early embryonic development. Development. 2015 Nov 15;142(22):3943-53
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5910434
Gene symbol: Bcas2
Gene name: BCAS2 pre-mRNA processing factor
Antibody: anti-BCAS2 (10414)
Detection system: Secondary antibody
Results
Specimen 1C GV: postnatal adult (more )
Note: Germinal vesicle oocytes.
Structure Level Pattern Image Note
TS28: primary oocyte Present 1C GV Expression is nuclear.
Specimen 1C MII: postnatal adult (more )
Note: Metaphase II oocytes.
Structure Level Pattern Image Note
TS28: secondary oocyte Present 1C MII Expression is cytoplasmic.
Specimen 1C 1C: embryonic day 0.5 (more )
Note: 1-cell zygote.
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Present 1C 1C Expression is nuclear.
Specimen 1C 2C: embryonic day 1.0 (more )
Note: 2-cell embryo.
Structure Level Pattern Image Note
TS2: 2-cell stage embryo Present 1C 2C Expression is nuclear.
Specimen 1C 4C: embryonic day 1.0 (more )
Note: 4-cell embryo.
Structure Level Pattern Image Note
TS3: 4-cell stage embryo Present 1C 4C Expression is nuclear.
Specimen 1C MO: embryonic day 3.0 (more )
Note: Morula stage embryo.
Structure Level Pattern Image Note
TS4: compacted morula Present 1C MO Expression is nuclear.
Specimen 1C BL: embryonic day 3.5 (more )
Note: Blastocyst stage embryo.
Structure Level Pattern Image Note
TS4: inner cell mass Present 1C BL Expression is nuclear.
Specimen 2A PN2: embryonic day 0.5 (more )
Note: 1-cell zygote 23 h post-hCG. Pronuclear stage 2. Double labeled: green - Bcas2; red - H2ax (assay MGI:5910436).
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Present 2A PN2 Merge , 2A PN2 BCAS2
Specimen 2A Mid PN3: embryonic day 0.5 (more )
Note: 1-cell zygote 25 h post-hCG. Pronuclear stage mid 3. Double labeled: green - Bcas2; red - H2ax (assay MGI:5910436).
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Present 2A Mid PN3 BCAS2 , 2A Mid PN3 Merge Expression is stronger in paternal pronuclei than in maternal pronuclei.
Specimen 2A PN4: embryonic day 0.5 (more )
Note: 1-cell zygote 28 h post-hCG. Pronuclear stage 4. Double labeled: green - Bcas2; red - H2ax (assay MGI:5910436).
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Present 2A PN4 BCAS2 , 2A PN4 Merge Expression is stronger in paternal pronuclei than in maternal pronuclei.
Specimen 2A late PN5: embryonic day 0.5 (more )
Note: 1-cell zygote 30 h post-hCG. Pronuclear stage late 5. Double labeled: green - Bcas2; red - H2ax (assay MGI:5910436).
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Present 2A Late PN5 BCAS2 , 2A Late PN5 Merge Expression is stronger in paternal pronuclei than in maternal pronuclei.
Specimen 2B PN2: embryonic day 0.5 (more )
Note: 1-cell zygote 23 h post-hCG. Pronuclear stage 2. Double labeled: green - Bcas2; red - H2ax (assay MGI:5910436). Specimens were treated with Triton for 1 minute prior to fixation.
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Present 2B PN2 BCAS2 , 2B PN2 Merge
Specimen 2B Late PN3: embryonic day 0.5 (more )
Note: 1-cell zygote 25 h post-hCG. Pronuclear stage late 3. Double labeled: green - Bcas2; red - H2ax (assay MGI:5910436). Specimens were treated with Triton for 1 minute prior to fixation.
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Present 2B Late PN3 BCAS2 , 2B Late PN3 Merge
Specimen 2B PN4: embryonic day 0.5 (more )
Note: 1-cell zygote 28 h post-hCG. Pronuclear stage 4. Double labeled: green - Bcas2; red - H2ax (assay MGI:5910436). Specimens were treated with Triton for 1 minute prior to fixation.
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Present 2B PN4 BCAS2 , 2B PN4 Merge
Specimen 2B Early PN5: embryonic day 0.5 (more )
Note: 1-cell zygote 30 h post-hCG. Pronuclear stage early 5. Double labeled: green - Bcas2; red - H2ax (assay MGI:5910436). Specimens were treated with Triton for 1 minute prior to fixation.
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Present 2B Early PN5 BCAS2 , 2B Early PN5 Merge
Specimen 2B Late PN5: embryonic day 0.5 (more )
Note: 1-cell zygote 30 h post-hCG. Pronuclear stage late 5. Double labeled: green - Bcas2; red - H2ax (assay MGI:5910436). Specimens were treated with Triton for 1 minute prior to fixation.
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Present 2B Late PN5 BCAS2 , 2B Late PN5 Merge
Specimen 3D Control: postnatal adult; Bcas2tm1.1Lil/Bcas2+, Tg(Zp3-cre)3Mrt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: germ cell of ovary Present 3D Control
Specimen 3D BcAs2mNull: postnatal adult; Bcas2tm1.1Lil/Bcas2tm1.1Lil, Tg(Zp3-cre)3Mrt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: germ cell of ovary Trace 3D Bcas2mNull
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory