Usp15em1Nki
Endonuclease-mediated Allele Detail
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| Symbol: |
Usp15em1Nki |
| Name: |
ubiquitin specific peptidase 15; endonuclease-mediated mutation 1, The Netherlands Cancer Institute |
| MGI ID: |
MGI:5810631 |
| Gene: |
Usp15 Location: Chr10:122940911-123032900 bp, - strand Genetic Position: Chr10, 72.31 cM, cytoband D3
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| Alliance: |
Usp15em1Nki page
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| Allele Type: |
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Endonuclease-mediated (Null/knockout) |
| Mutation: |
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Intragenic deletion
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Mutation details: CRISPR/Cas9 system was used to generate a 91,795 bp deletion using 5 gRNA cut at Chr10:123,196,931 upstream of exon 1 and a 3 gRNA cut at Chr10:123,105,136, downstream of the last exon, exon 22. The sequence at the fusion point is: gccgccgcctccgctaTcGGatcgtatcaagtgacat (capital letters: different from expected fusion product).
(J:306500)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Usp15 Mutation: |
60 strains or lines available
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| Original: |
J:306500 van den Berk P, et al., USP15 Deubiquitinase Safeguards Hematopoiesis and Genome Integrity in Hematopoietic Stem Cells and Leukemia Cells. Cell Rep. 2020 Dec 29;33(13):108533 |
| All: |
1 reference(s) |
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Analysis Tools
