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Gene Expression Data
Assay Details
Assay
Reference: J:193529 Aguado C, et al., Differential maturation of GIRK2-expressing neurons in the mouse cerebellum. J Chem Neuroanat. 2013 Jan;47:79-89
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5707612
Gene symbol: Kcnj6
Gene name: potassium inwardly-rectifying channel, subfamily J, member 6
Antibody: Anti-Girk2
Detection system: Secondary antibody
Results
Specimen 3A: embryonic day 18.0 (more )
Note: Double labeled: red - Kcnj6; green - Pax6 (assay MGI:5707616).
Structure Level Pattern Image Note
TS26: cerebellum external granule cell layer Present Regionally restricted 3A3 , 3A1 Expression was detected in the inner part of the external granule cell layer. The outer part of the external granule cell layer was negative.
TS26: cerebellum Present Regionally restricted 3A1 , 3A3 Expression deeper in the cerebellar anlage and inner granule cell layer co-expressed Pax6. There was no co-expression with Pax6 in the rhombic lip.

Specimen 3B,D: embryonic day 18.0 (more )
Note: Double labeled: red - Kcnj6; green - Pax6 (assay MGI:5707616).
Structure Level Pattern Image Note
TS26: cerebellum external granule cell layer Present Regionally restricted 3B1 , 3B3 Expression was detected in the inner part of the external granule cell layer. The outer part of the external granule cell layer was negative.
TS26: cerebellum Present Regionally restricted 3D3 , 3D1 , 3B3 , 3B1 Expression deeper in the cerebellar anlage and inner granule cell layer co-expressed Pax6.

Specimen 3C: embryonic day 18.0 (more )
Note: Double labeled: red - Kcnj6; green - Pax6 (assay MGI:5707616).
Structure Level Pattern Image Note
TS26: cerebellum external granule cell layer Present Regionally restricted 3C1 , 3C3 Expression was detected in the inner part of the external granule cell layer. The outer part of the external granule cell layer was negative.
TS26: cerebellum Present Regionally restricted 3C3 , 3C1 Expression deeper in the cerebellar anlage and inner granule cell layer co-expressed Pax6. There was no co-expression with Pax6 in the rhombic lip.

Specimen 6A: postnatal adult; Gad1tm1.1Tama/Gad1+ (more )
Note: Triple labeled: red - Kcnj6; blue - Nrgn (assay MGI:5707687); green - Gad1 (assay MGI:5707688).
Structure Level Pattern Image Note
TS28: cerebellum granule cell layer Present Regionally restricted 6A4 , 6A1 Co-expression was noted with Gad1 and Nrgn.

Specimen 6B: postnatal adult; Gad1tm1.1Tama/Gad1+ (more )
Note: Triple labeled: red - Kcnj6; blue - Nrgn (assay MGI:5707687); green - Gad1 (assay MGI:5707688).
Structure Level Pattern Image Note
TS28: cerebellum granule cell layer Present Regionally restricted 6B1 , 6B4 Co-expression was noted with Gad1 and Nrgn.

Specimen 6C: postnatal adult; Gad1tm1.1Tama/Gad1+ (more )
Note: Triple labeled: red - Kcnj6; blue - Grm2 (assay MGI:5707691) and Grm3 (assay MGI:5707694); green - Gad1 (assay MGI:5707688).
Structure Level Pattern Image Note
TS28: cerebellum granule cell layer Present Regionally restricted 6C1 , 6C4 Co-expression was noted with Gad1 and Grm2/3 in some cells.

Specimen 6D: postnatal adult; Gad1tm1.1Tama/Gad1+ (more )
Note: Triple labeled: red - Kcnj6; blue - Grm2 (assay MGI:5707691) and Grm3 (assay MGI:5707694); green - Gad1 (assay MGI:5707688).
Structure Level Pattern Image Note
TS28: cerebellum granule cell layer Present Regionally restricted 6D4 , 6D1 Co-expression was noted with Gad1 only in some cells.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory