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Gene Expression Data
Assay Details
Assay
Reference: J:202990 Lehigh KM, et al., Parcellation of the thalamus into distinct nuclei reflects EphA expression and function. Gene Expr Patterns. 2013 Dec;13(8):454-63
Assay type: RNA in situ
MGI Accession ID: MGI:5696231
Gene symbol: Efna5
Gene name: ephrin A5
Probe: EphrinA5 cDNA1
Probe preparation: labelled with radioactivity
Results
Specimen 1H/J: embryonic day 14.5 (more )
Note: Wild type mice were either CD-1 or C57BL/6. Pseudocolored and overlaid: green - Efna5; red - Epha7 (assay MGI:5696230); red - Epha4 (assay MGI:5695630).
Structure Level Pattern Image Note
TS22: thalamus Present Regionally restricted 1J , 1H Expression was detected at the dorsal and ventral edges of the dorsal thalamus. Expression was largely distinct from cells expressing Epha4 and Epha7.
Specimen 2D/F: embryonic day 15.5 (more )
Note: Wild type mice were either CD-1 or C57BL/6. Pseudocolored and overlaid: green - Efna5; red - Epha7 (assay MGI:5696230); red - Epha4 (assay MGI:5695630).
Structure Level Pattern Image Note
TS23: thalamus Weak Regionally restricted 2D , 2F There was colocalization with Epha4 in the anterior region of the dorsal thalamus and in ventral structures.
TS23: prethalamus Present 2D , 2F
TS23: reticular thalamic nucleus Present 2D , 2F
TS23: zona incerta Present 2D , 2F
Specimen 3D/F: embryonic day 17.5 (more )
Note: Wild type mice were either CD-1 or C57BL/6. Pseudocolored and overlaid: green - Efna5; red - Epha7 (assay MGI:5696230); red - Epha4 (assay MGI:5695630).
Structure Level Pattern Image Note
TS25: reticular thalamic nucleus Present 3F , 3D
TS25: ventral lateral geniculate nucleus Present 3F , 3D
TS25: zona incerta Present 3F , 3D
TS25: thalamus Present Regionally restricted 3D , 3F Expressing cells did not show overlap with Epha7.
TS25: posterior thalamic nucleus Present Regionally restricted 3D , 3F Expression was detected at the ventral edge of the ventral posterior nucleus. There was overlap with Epha4 in a lateral portion.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory