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Gene Expression Data
Assay Details
Assay
Reference: J:202990 Lehigh KM, et al., Parcellation of the thalamus into distinct nuclei reflects EphA expression and function. Gene Expr Patterns. 2013 Dec;13(8):454-63
Assay type: RNA in situ
MGI Accession ID: MGI:5696230
Gene symbol: Epha7
Gene name: Eph receptor A7
Probe: Epha7 cDNA1
Probe preparation: labelled with radioactivity
Results
Specimen 1C/D: embryonic day 12.5 (more )
Note: Wild type mice were either CD-1 or C57BL/6. Pseudocolored and overlaid: green - Epha7; red - Epha4 (assay MGI:5695630).
Structure Level Pattern Image Note
TS20: epithalamus Present 1D , 1C There was some colocalization with EphA4.
TS20: prosomere 2 Present 1D , 1C There was some colocalization with EphA4.
TS20: thalamus Present 1D , 1C There was some colocalization with EphA4.
Specimen 1G/I/J: embryonic day 14.5 (more )
Note: Wild type mice were either CD-1 or C57BL/6. Pseudocolored and overlaid (I,J): green (I)/red (J) - Epha7; red - Epha4 (assay MGI:5695630); green - Efna5 (assay MGI:5696231).
Structure Level Pattern Image Note
TS22: thalamus Present Regionally restricted 1I , 1J , 1G Expression was detected in discrete portions of the positive expression domain of Epha4. Expression was largely distinct from cells expressing Efna5.
Specimen 2C,E,F: embryonic day 15.5 (more )
Note: Wild type mice were either CD-1 or C57BL/6. Pseudocolored and overlaid (E,F): green (E)/red (F) - Epha7; red - Epha4 (assay MGI:5695630); green - Efna5 (assay MGI:5696231).
Structure Level Pattern Image Note
TS23: prethalamus Present Graded 2F , 2E , 2C Expression was diffuse with a posterior-high gradient.
TS23: thalamus Present Graded 2F , 2E , 2C Expression was diffuse with a posterior-high gradient.
TS23: zona incerta Present Graded 2F , 2E , 2C Expression was diffuse with a posterior-high gradient.
Specimen 3C,E,F: embryonic day 17.5 (more )
Note: Wild type mice were either CD-1 or C57BL/6. Pseudocolored and overlaid (E,F): green (E)/red (F) - Epha7; red - Epha4 (assay MGI:5695630); green - Efna5 (assay MGI:5696231).
Structure Level Pattern Image Note
TS25: thalamus Present Regionally restricted 3F , 3E , 3C Predominantly medioventrally expressed. There was overlap in the domains of Epha4 and Epha7, but no overlap with Efna5.
TS25: ventral lateral geniculate nucleus Present 3E , 3F , 3C
TS25: posterior thalamic nucleus Present Regionally restricted 3F , 3E , 3C Expression was detected in a medial portion of the posterior nucleus, as well as the ventral posterior nucleus.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory