Uncx RNA in situ Gene Expression Assay - GXD

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Gene Expression Data
Assay Details

Assay

Reference:	J:155226 Andersson ER, et al., Genetic interaction between Lrp6 and Wnt5a during mouse development. Dev Dyn. 2009 Sep 30;239(1):237-245
Assay type:	RNA in situ
MGI Accession ID:	MGI:5568342
Gene symbol:	Uncx
Gene name:	UNC homeobox

Probe:	Uncx4.1 cDNA1
Probe preparation:	Antisense RNA

Results

3c left panel ©

Specimen 3C left panel: embryonic day 9.5 (more

)

Structure	Level	Pattern	Image	Note
TS15: somite	Present		3c left panel

3c middle panel ©

Specimen 3C middle panel: embryonic day 9.5; Wnt5a^tm1Amc/Wnt5a^tm1Amc (more

)

Structure	Level	Pattern	Image	Note
TS15: somite	Present		3c middle panel

3c right panel ©

Specimen 3C right panel: embryonic day 9.5; Lrp6^Gt(Ex187)Byg/Lrp6⁺, Wnt5a^tm1Amc/Wnt5a^tm1Amc (more

)

Structure	Level	Pattern	Image	Note
TS15: somite	Present		3c right panel	There is a slight reduction in the number of somites in this mutant.

4A Wnt5a+/+;Lrp6+/+ ©

Specimen 4A Wnt5a+;+;Lrp6+/+: embryonic day 8.5 (more

)
Note: Double labeled: brown - Uncx; purple - Hes7 (assay MGI:5568351).

Structure	Level	Pattern	Image	Note
TS13: somite	Present		4A Wnt5a+/+;Lrp6+/+

4A Wnt5a-/-;Lrp6+/+ ©

Specimen 4A Wnt5a-/-;Lrp6+/+: embryonic day 8.5; Wnt5a^tm1Amc/Wnt5a^tm1Amc (more

)
Note: Double labeled: brown - Uncx; purple - Hes7 (assay MGI:5568351).

Structure	Level	Pattern	Image	Note
TS13: somite	Present		4A Wnt5a-/-;Lrp6+/+

4A Wnt5a+/+;Lrp6-/- ©

Specimen 4A Wnt5a+/+;Lrp6-/-: embryonic day 8.5; Lrp6^Gt(Ex187)Byg/Lrp6^Gt(Ex187)Byg (more

)
Note: Double labeled: brown - Uncx; purple - Hes7 (assay MGI:5568351).

Structure	Level	Pattern	Image	Note
TS13: somite	Weak		4A Wnt5a+/+;Lrp6-/-

4A #1 ©

Specimen 4A #1: embryonic day 8.5; Lrp6^Gt(Ex187)Byg/Lrp6^Gt(Ex187)Byg, Wnt5a^tm1Amc/Wnt5a^tm1Amc (more

)
Note: Double labeled: brown - Uncx; purple - Hes7 (assay MGI:5568351).

Structure	Level	Pattern	Image	Note
TS13: somite	Present	Regionally restricted	4A #1	In anterior segmented somites expression is striped and in posterior somites it is fused.

4A #2 ©

Specimen 4A #2: embryonic day 8.5; Lrp6^Gt(Ex187)Byg/Lrp6^Gt(Ex187)Byg, Wnt5a^tm1Amc/Wnt5a^tm1Amc (more

)
Note: Double labeled: brown - Uncx; purple - Hes7 (assay MGI:5568351).

Structure	Level	Pattern	Image	Note
TS13: somite	Present	Regionally restricted	4A #2	In anterior segmented somites expression is striped and in posterior somites it is fused.

4A #3 ©

Specimen 4A #3: embryonic day 8.5; Lrp6^Gt(Ex187)Byg/Lrp6^Gt(Ex187)Byg, Wnt5a^tm1Amc/Wnt5a^tm1Amc (more

)
Note: Double labeled: brown - Uncx; purple - Hes7 (assay MGI:5568351).

Structure	Level	Pattern	Image	Note
TS13: somite	Present	Regionally restricted	4A #3	In anterior segmented somites expression is striped and in posterior somites it is fused.

4A Wnt5a+/-;Lrp6-/- ©

Specimen 4A Wnt5a+/-;Lrp6-/-: embryonic day 8.5; Lrp6^Gt(Ex187)Byg/Lrp6^Gt(Ex187)Byg, Wnt5a^tm1Amc/Wnt5a⁺ (more

)
Note: Double labeled: brown - Uncx; purple - Hes7 (assay MGI:5568351).

Structure	Level	Pattern	Image	Note
TS13: trunk unsegmented mesenchyme	Weak	Regionally restricted	4A Wnt5a+/-;Lrp6-/-

4A Wnt5a-/-/Lrp6+/- ©

Specimen 4A Wnt5a-/-;Lrp6+/-: embryonic day 8.5; Lrp6^Gt(Ex187)Byg/Lrp6⁺, Wnt5a^tm1Amc/Wnt5a^tm1Amc (more

)
Note: Double labeled: brown - Uncx; purple - Hes7 (assay MGI:5568351).

Structure	Level	Pattern	Image	Note
TS13: somite	Present		4A Wnt5a-/-/Lrp6+/-
TS13: trunk unsegmented mesenchyme	Present		4A Wnt5a-/-/Lrp6+/-

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