Gene Expression Data
Assay Details
|
Assay
|
|
Reference:
|
J:164344
Lecoin L, et al., MafA transcription factor identifies the early ret-expressing sensory neurons. Dev Neurobiol. 2010 Jun;70(7):485-97
|
|
Assay type:
|
In situ reporter (knock in)
|
|
MGI Accession ID:
|
MGI:4943476
|
|
Gene symbol:
|
Mafa
|
|
Gene name:
|
MAF bZIP transcription factor A
|
|
Reporter:
|
lacZ
|
|
|
Direct Detection
|
|
|
Results
|
Specimen
1B:
(close  )
|
Genetic Background:
|
either: (involves: 129 * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
|
|
Mutant Allele(s):
|
Mafatm1.1Eyc/Mafa+
|
|
Age:
|
embryonic day 8.0
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
1C:
(close )
|
Genetic Background:
|
either: (involves: 129 * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
|
|
Mutant Allele(s):
|
Mafatm1.1Eyc/Mafa+
|
|
Age:
|
embryonic day 8.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
1D:
(close )
|
Genetic Background:
|
either: (involves: 129 * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
|
|
Mutant Allele(s):
|
Mafatm1.1Eyc/Mafa+
|
|
Age:
|
embryonic day 9.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS16: neural tube |
Present |
Regionally restricted |
1D
|
Expression is present in the ventral neural tube.
|
Specimen
1E:
(close )
|
Genetic Background:
|
either: (involves: 129 * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
|
|
Mutant Allele(s):
|
Mafatm1.1Eyc/Mafa+
|
|
Age:
|
embryonic day 11.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
1F:
(close )
|
Genetic Background:
|
either: (involves: 129 * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
|
|
Mutant Allele(s):
|
Mafatm1.1Eyc/Mafa+
|
|
Age:
|
embryonic day 12.0
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
1G:
(close )
|
Genetic Background:
|
either: (involves: 129 * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
|
|
Mutant Allele(s):
|
Mafatm1.1Eyc/Mafa+
|
|
Age:
|
embryonic day 14.0
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
1H:
(close )
|
Genetic Background:
|
either: (involves: 129 * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
|
|
Mutant Allele(s):
|
Mafatm1.1Eyc/Mafa+
|
|
Age:
|
embryonic day 9.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
1I:
(close )
|
Genetic Background:
|
either: (involves: 129 * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
|
|
Mutant Allele(s):
|
Mafatm1.1Eyc/Mafa+
|
|
Age:
|
embryonic day 10.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
2A:
(close )
|
Genetic Background:
|
either: (involves: 129 * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
|
|
Mutant Allele(s):
|
Mafatm1.1Eyc/Mafa+
|
|
Age:
|
embryonic day 12.0
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
2B/D:
embryonic day 12.0; Mafatm1.1Eyc/Mafa +
(more  )
Note: Double labeled: blue - Mafa reporter; yellow/green- Mafa protein (assay MGI:4943480).
Specimen
2B/D:
(close )
|
Genetic Background:
|
either: (involves: 129 * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
|
|
Mutant Allele(s):
|
Mafatm1.1Eyc/Mafa+
|
|
Age:
|
embryonic day 12.0
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Note:
|
Double labeled: blue - Mafa reporter; yellow/green- Mafa protein (assay MGI:4943480).
|
Specimen
2G:
(close )
|
Genetic Background:
|
either: (involves: 129 * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
|
|
Mutant Allele(s):
|
Mafatm1.1Eyc/Mafa+
|
|
Age:
|
embryonic day 12.0
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
2J:
(close )
|
Genetic Background:
|
either: (involves: 129 * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
|
|
Mutant Allele(s):
|
Mafatm1.1Eyc/Mafa+
|
|
Age:
|
embryonic day 16.0
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
4 Ret:
embryonic day 11.5; Mafatm1.1Eyc/Mafa +
(more )
Note: Double labeled: blue - Mafa; brown - Ret (assay MGI:4943506).
Specimen
4 Ret:
(close )
|
Genetic Background:
|
either: (involves: 129 * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
|
|
Mutant Allele(s):
|
Mafatm1.1Eyc/Mafa+
|
|
Age:
|
embryonic day 11.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Note:
|
Double labeled: blue - Mafa; brown - Ret (assay MGI:4943506).
|
Specimen
4 Ret:
embryonic day 12.5; Mafatm1.1Eyc/Mafa +
(more )
Note: Double labeled: blue - Mafa; brown - Ret (assay MGI:4943506).
Specimen
4 Ret:
(close )
|
Genetic Background:
|
either: (involves: 129 * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
|
|
Mutant Allele(s):
|
Mafatm1.1Eyc/Mafa+
|
|
Age:
|
embryonic day 12.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Note:
|
Double labeled: blue - Mafa; brown - Ret (assay MGI:4943506).
|
Specimen
4 Ret:
embryonic day 13.5; Mafatm1.1Eyc/Mafa +
(more )
Note: Double labeled: blue - Mafa; brown - Ret (assay MGI:4943506).
Specimen
4 Ret:
(close )
|
Genetic Background:
|
either: (involves: 129 * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
|
|
Mutant Allele(s):
|
Mafatm1.1Eyc/Mafa+
|
|
Age:
|
embryonic day 13.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Note:
|
Double labeled: blue - Mafa; brown - Ret (assay MGI:4943506).
|
Specimen
4 Ret:
embryonic day 15.5; Mafatm1.1Eyc/Mafa +
(more )
Note: Double labeled: blue - Mafa; brown - Ret (assay MGI:4943506).
Specimen
4 Ret:
(close )
|
Genetic Background:
|
either: (involves: 129 * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
|
|
Mutant Allele(s):
|
Mafatm1.1Eyc/Mafa+
|
|
Age:
|
embryonic day 15.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Note:
|
Double labeled: blue - Mafa; brown - Ret (assay MGI:4943506).
|
Specimen
4 TrkB:
embryonic day 11.5; Mafatm1.1Eyc/Mafa +
(more )
Note: Double labeled: blue - Mafa; brown - Ntrk2 (assay MGI:4943507).
Specimen
4 TrkB:
(close )
|
Genetic Background:
|
either: (involves: 129 * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
|
|
Mutant Allele(s):
|
Mafatm1.1Eyc/Mafa+
|
|
Age:
|
embryonic day 11.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Note:
|
Double labeled: blue - Mafa; brown - Ntrk2 (assay MGI:4943507).
|
Specimen
4 TrkB:
embryonic day 12.5; Mafatm1.1Eyc/Mafa +
(more )
Note: Double labeled: blue - Mafa; brown - Ntrk2 (assay MGI:4943507).
Specimen
4 TrkB:
(close )
|
Genetic Background:
|
either: (involves: 129 * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
|
|
Mutant Allele(s):
|
Mafatm1.1Eyc/Mafa+
|
|
Age:
|
embryonic day 12.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Note:
|
Double labeled: blue - Mafa; brown - Ntrk2 (assay MGI:4943507).
|
Specimen
4 TrkB:
embryonic day 13.5; Mafatm1.1Eyc/Mafa +
(more )
Note: Double labeled: blue - Mafa; brown - Ntrk2 (assay MGI:4943507).
Specimen
4 TrkB:
(close )
|
Genetic Background:
|
either: (involves: 129 * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
|
|
Mutant Allele(s):
|
Mafatm1.1Eyc/Mafa+
|
|
Age:
|
embryonic day 13.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Note:
|
Double labeled: blue - Mafa; brown - Ntrk2 (assay MGI:4943507).
|
Specimen
4 TrkB:
embryonic day 15.5; Mafatm1.1Eyc/Mafa +
(more )
Note: Double labeled: blue - Mafa; brown - Ntrk2 (assay MGI:4943507).
Specimen
4 TrkB:
(close )
|
Genetic Background:
|
either: (involves: 129 * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
|
|
Mutant Allele(s):
|
Mafatm1.1Eyc/Mafa+
|
|
Age:
|
embryonic day 15.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Note:
|
Double labeled: blue - Mafa; brown - Ntrk2 (assay MGI:4943507).
|
Specimen
4 TrkC:
embryonic day 11.5; Mafatm1.1Eyc/Mafa +
(more )
Note: Double labeled: blue - Mafa; brown - Ntrk3 (assay MGI:4943508).
Specimen
4 TrkC:
(close )
|
Genetic Background:
|
either: (involves: 129 * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
|
|
Mutant Allele(s):
|
Mafatm1.1Eyc/Mafa+
|
|
Age:
|
embryonic day 11.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Note:
|
Double labeled: blue - Mafa; brown - Ntrk3 (assay MGI:4943508).
|
Specimen
4 TrkC:
embryonic day 12.5; Mafatm1.1Eyc/Mafa +
(more )
Note: Double labeled: blue - Mafa; brown - Ntrk3 (assay MGI:4943508).
Specimen
4 TrkC:
(close )
|
Genetic Background:
|
either: (involves: 129 * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
|
|
Mutant Allele(s):
|
Mafatm1.1Eyc/Mafa+
|
|
Age:
|
embryonic day 12.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Note:
|
Double labeled: blue - Mafa; brown - Ntrk3 (assay MGI:4943508).
|
Specimen
4 TrkC:
embryonic day 13.5; Mafatm1.1Eyc/Mafa +
(more )
Note: Double labeled: blue - Mafa; brown - Ntrk3 (assay MGI:4943508).
Specimen
4 TrkC:
(close )
|
Genetic Background:
|
either: (involves: 129 * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
|
|
Mutant Allele(s):
|
Mafatm1.1Eyc/Mafa+
|
|
Age:
|
embryonic day 13.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Note:
|
Double labeled: blue - Mafa; brown - Ntrk3 (assay MGI:4943508).
|
Specimen
4 TrkC:
embryonic day 15.5; Mafatm1.1Eyc/Mafa +
(more )
Note: Double labeled: blue - Mafa; brown - Ntrk3 (assay MGI:4943508).
Specimen
4 TrkC:
(close )
|
Genetic Background:
|
either: (involves: 129 * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
|
|
Mutant Allele(s):
|
Mafatm1.1Eyc/Mafa+
|
|
Age:
|
embryonic day 15.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Note:
|
Double labeled: blue - Mafa; brown - Ntrk3 (assay MGI:4943508).
|
Specimen
5A:
(close )
|
Genetic Background:
|
either: (involves: 129/Sv * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
|
|
Mutant Allele(s):
|
Mafatm1.1Eyc/Mafatm1.1Eyc
|
|
Age:
|
embryonic day 12.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
5B:
(close )
|
Genetic Background:
|
either: (involves: 129 * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
|
|
Mutant Allele(s):
|
Mafatm1.1Eyc/Mafa+
|
|
Age:
|
embryonic day 12.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
5D:
(close )
|
Genetic Background:
|
either: (involves: 129/Sv * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
|
|
Mutant Allele(s):
|
Mafatm1.1Eyc/Mafatm1.1Eyc
|
|
Age:
|
embryonic day 15.0
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS23: dorsal root ganglion |
Present |
Single cells |
5D
|
The number of expressing cells found in homozygotes is similar to the number found in heterozygotes.
|
Specimen
5E:
(close )
|
Genetic Background:
|
either: (involves: 129 * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
|
|
Mutant Allele(s):
|
Mafatm1.1Eyc/Mafa+
|
|
Age:
|
embryonic day 15.0
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
6A:
(close )
|
Genetic Background:
|
either: (involves: 129/Sv * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
|
|
Mutant Allele(s):
|
Mafatm1.1Eyc/Mafatm1.1Eyc
|
|
Age:
|
postnatal week 6
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: dorsal root ganglion |
Present |
|
6A
|
The number of expressing cells found in homozygotes is similar to the number found in heterozygotes.
|
Specimen
6B:
(close )
|
Genetic Background:
|
either: (involves: 129/Sv * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
|
|
Mutant Allele(s):
|
Mafatm1.1Eyc/Mafatm1.1Eyc
|
|
Age:
|
postnatal week 6
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Note:
|
Double labeled: blue - Mafa; brown - Ret (assay MGI:4943506).
|
Specimen
6D:
(close )
|
Genetic Background:
|
either: (involves: 129 * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
|
|
Mutant Allele(s):
|
Mafatm1.1Eyc/Mafa+
|
|
Age:
|
postnatal week 6
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
6E:
postnatal week 6; Mafatm1.1Eyc/Mafa +
(more )
Note: Double labeled: blue - Mafa; brown - Ret (assay MGI:4943506).
Specimen
6E:
(close )
|
Genetic Background:
|
either: (involves: 129 * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
|
|
Mutant Allele(s):
|
Mafatm1.1Eyc/Mafa+
|
|
Age:
|
postnatal week 6
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Note:
|
Double labeled: blue - Mafa; brown - Ret (assay MGI:4943506).
|
Specimen
S2 O:
(close )
|
Genetic Background:
|
either: (involves: 129 * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
|
|
Mutant Allele(s):
|
Mafatm1.1Eyc/Mafa+
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
S2 P:
(close )
|
Genetic Background:
|
either: (involves: 129/Sv * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
|
|
Mutant Allele(s):
|
Mafatm1.1Eyc/Mafatm1.1Eyc
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Analysis Tools