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Gene Expression Data
Assay Details
Assay
Reference: J:103820 Reiter JF, et al., Tectonic, a novel regulator of the Hedgehog pathway required for both activation and inhibition. Genes Dev. 2006 Jan 1;20(1):22-7
Assay type: Immunohistochemistry
MGI Accession ID: MGI:4462009
Gene symbol: Nkx2-2
Gene name: NK2 homeobox 2
Antibody: 74.5A5
Results
Specimen 3C wild type: embryonic day 9.5 (more )
Note: Double labeled: green - Nkx2-2; red - Pax6 (assay MGI:4461989).
Structure Level Pattern Image Note
TS15: neural tube Present Regionally restricted 3C wild type Expression was detected in the progenitors of the V3 interneurons (p3).
Specimen 3C Tectonic-/-: embryonic day 9.5; Tctn1Gt(KST296)Byg/Tctn1Gt(KST296)Byg (more )
Note: Double labeled: green - Nkx2-2; red - Pax6 (assay MGI:4461989).
Structure Level Pattern Image Note
TS15: neural tube Absent 3C Tectonic-/- Expression was not detected in the progenitors of the V3 interneurons (p3).
Specimen 3C Ptch-/-: embryonic day 9.5; Ptch1tm1Mps/Ptch1tm1Mps (more )
Note: Double labeled: green - Nkx2-2; red - Pax6 (assay MGI:4461989).
Structure Level Pattern Image Note
TS15: neural tube Present 3C Ptch-/- Expression in the mutant was expanded compared to wild type.
Specimen 3C Tectonic-/- Ptch-/-: embryonic day 9.5; Ptch1tm1Mps/Ptch1tm1Mps, Tctn1Gt(KST296)Byg/Tctn1Gt(KST296)Byg (more )
Note: Double labeled: green - Nkx2-2; red - Pax6 (assay MGI:4461989).
Structure Level Pattern Image Note
TS15: neural tube Absent 3C Tectonic-/- Ptch-/- Expression was not detected in the progenitors of the V3 interneurons (p3).
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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