About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:118937 Kaji K, et al., Mbd3, a component of the NuRD co-repressor complex, is required for development of pluripotent cells. Development. 2007 Mar;134(6):1123-32
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3703707
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-activated Caspase 3 (AF835)
Detection system: Secondary antibody
Results
Specimen S1 +/+: embryonic day 5.5 (more )
Note: Double labeled: green - activated Casp3; red - Pou5f1 (assay MGI:3703637).
Structure Level Pattern Image Note
TS8: embryo Present S1A +/+

Specimen S1 +/-: embryonic day 5.5; Mbd3tm1Bh/Mbd3+ (more )
Note: Double labeled: green - activated Casp3; red - Pou5f1 (assay MGI:3703637).
Structure Level Pattern Image Note
TS8: embryo Present S1A +/-

Specimen S1 -/- left: embryonic day 5.5; Mbd3tm1Bh/Mbd3tm1Bh (more )
Note: Double labeled: green - activated Casp3; red - Pou5f1 (assay MGI:3703637).
Structure Level Pattern Image Note
TS8: embryo Present S1A -/- left Expression in this mutant is the same as in wild-type embryos.

Specimen S1 -/- right: embryonic day 5.5; Mbd3tm1Bh/Mbd3tm1Bh (more )
Note: Double labeled: green - activated Casp3; red - Pou5f1 (assay MGI:3703637).
Structure Level Pattern Image Note
TS8: embryo Present S1A -/- right Expression in this mutant is the same as in wild-type embryos.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory