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Gene Expression Data
Assay Details
Assay
Reference: J:82456 Gianino S, et al., GDNF availability determines enteric neuron number by controlling precursor proliferation. Development. 2003 May;130(10):2187-98
Assay type: Immunohistochemistry
MGI Accession ID: MGI:2675160
Gene symbol: Uchl1
Gene name: ubiquitin carboxy-terminal hydrolase L1
Antibody: Anti-PGP9.5
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 3B: embryonic day 14.5 (more )
Note: Double labeled: red - Uchl1; green - Gfra2 (assay MGI:2675154).
Structure Level Pattern Image Note
TS22: peripheral nervous system Present Single cells 3B Expression was detected in the neural crest cells in the gut.
Specimen 6A: embryonic day 12.5 (more )
Note: Double labeled: red - Uchl1; green - BrdU.
Structure Level Pattern Image Note
TS20: enteric nervous system Present Single cells 6A Expression was detected in the enteric nervous system (ENS) neuronal precursors in the gut.
Specimen 6B: embryonic day 12.5; Gdnftm1Rosl/Gdnf+ (more )
Note: Double labeled: red - Uchl1; green - BrdU.
Structure Level Pattern Image Note
TS20: enteric nervous system Present Single cells 6B Expression was detected in the enteric nervous system (ENS) neuronal precursors in the gut. Proliferation of these neuronal precursors was lower in the heterozygous animal compared to wild type as indicated by BrdU incorporation.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory