Mip<Cat> Spontaneous Allele Detail MGI Mouse (MGI:1856474)

Mip^Cat
Spontaneous Allele Detail

Summary

Symbol:	Mip^Cat
Name:	major intrinsic protein of lens fiber; dominant cataract
MGI ID:	MGI:1856474
Synonyms:	cataracta hereditaria subcapsularis
Gene:	Mip Location: Chr10:128061707-128067681 bp, + strand Genetic Position: Chr10, 76.49 cM, cytoband D1
Alliance:	Mip^Cat page

Mutation
origin

Strain of Origin:

albino stock

Mutation
description

Allele Type:		Spontaneous
Mutation:		Transposon insertion
Inheritance:		Semidominant

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Mip Mutation:	31 strains or lines available

Notes

This mutation was first described, under the imposing name cataracta hereditaria subcapsularis, in an albino strain of unknown origin (J:285). The probably identical "cataract Fraser" allele, Mip^Cat-Fr, was found in the A/J strain. Most of the studies characterizing these cataract causing mutations in Mip have been carried out using Mip^Cat-Fr, and are described under that mutation.

References

Original:	J:285 PAGET OE, [Hereditary subcapsular cataract; a new dominant allelomorph in house mouse.]. Z Indukt Abstamm Vererbungsl. 1953;85(2):238-44
All:	1 reference(s)

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