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Gene Expression Data
Assay Details
Assay
Reference: J:58081 Lettice L, et al., The dominant hemimelia mutation uncouples epithelial-mesenchymal interactions and disrupts anterior mesenchyme formation in mouse hindlimbs. Development. 1999 Nov;126(21):4729-36
Assay type: RNA in situ
MGI Accession ID: MGI:1349145
Gene symbol: Shh
Gene name: sonic hedgehog
Probe: Shh probe17
Probe preparation: Antisense labelled with fluorescein RNA
Results
Specimen 3D +/+: embryonic day 11.5 (more )
Note: Double labeled: blue - Shh; purple - Fgf8 (assay MGI:1349142).
Structure Level Pattern Image Note
TS19: footplate mesenchyme Present Regionally restricted 3D Expression is at the posterior margin.
Specimen 3E Dh/+: embryonic day 11.5; Dh/Dh+ (more )
Note: Double labeled: blue - Shh; purple - Fgf8 (assay MGI:1349142).
Structure Level Pattern Image Note
TS19: footplate mesenchyme Present Regionally restricted 3E Expression in this mutant is similar to that of wild-type.
Specimen 3F Dh/Dh: embryonic day 11.5; Dh/Dh (more )
Note: Double labeled: blue - Shh; purple - Fgf8 (assay MGI:1349142).
Structure Level Pattern Image Note
TS19: footplate mesenchyme Present Regionally restricted 3F The posterior expression in this mutant is similar to that of wild-type embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
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